Results 71 to 80 of about 4,818,434 (320)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Multinomial Regression with Elastic Net Penalty and Its Grouping Effect in Gene Selection

open access: yesAbstract and Applied Analysis, 2014
For the multiclass classification problem of microarray data, a new optimization model named multinomial regression with the elastic net penalty was proposed in this paper.
Liuyuan Chen   +3 more
doaj   +1 more source

A time-course prediction model of global COVID-19 mortality

open access: yesFrontiers in Public Health, 2023
IntroductionThe COVID-19 pandemic has caused over 6 million deaths worldwide and is a significant cause of mortality. Mortality dynamics vary significantly by country due to pathogen, host, social and environmental factors, in addition to vaccination and
Mark Ciaccio   +8 more
doaj   +1 more source

The elastic behavior of entropic "fisherman's net” [PDF]

open access: yesThe European Physical Journal E, 2000
A new formalism is used for a Monte Carlo determination of the elastic constants of a two-dimensional net of fixed connectivity. The net is composed of point-like atoms each of which is tethered to six neighbors by a bond limiting the distance between them to a certain maximal separation, but having zero energy at all smaller lengths.
Farago, Oded, Kantor, Yacov
openaire   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Asymptotic Level Density of the Elastic Net Self-Organizing Feature Map

open access: yes, 2002
Whileas the Kohonen Self Organizing Map shows an asymptotic level density following a power law with a magnification exponent 2/3, it would be desired to have an exponent 1 in order to provide optimal mapping in the sense of information theory.
D. R. Dersch   +11 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Wheat yield prediction based on weather parameters using multiple linear, neural network and penalised regression models

open access: yesJournal of Agrometeorology, 2022
Wheat yield production is largely attributed by weather parameters. Model developed by multiple linear, neural network and penalised regression techniques using weather data have the potential to provide reliable, timely and cost-effective prediction of
K. S. ARAVIND   +3 more
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Degradation Pattern Identification and Remaining Useful Life Prediction for Mechanical Equipment Using SKF-EN

open access: yesIEEE Access, 2020
Due to the influence of working environment and stress, the failure degradation process of mechanical equipment is characterized by non-stationarity and uncertainty. The degradation pattern of a large number of mechanical equipment obeys the process from
Shenglong Wang   +3 more
doaj   +1 more source

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