Results 11 to 20 of about 11,334 (149)

A Fully Automatic and Efficient Methodology for Peptide Activity Identification Using Their 3D Conformations

IEEE Access, 2021
Over the past decades, the understanding of peptides and proteins biological functions has been an active research topic. Latest research works in this field have suggested that protein conformations may be a key feature for gaining insights into protein
Azzam Alwan, Remi Cogranne, Pierre Beauseroy, Edith Grall-Maes, Nicolas Belloy, Laurent Debelle, Stephanie Baud, Manuel Dauchez, Sebastien Almagro   +8 more
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Targeted delivery of pentagalloyl glucose inhibits matrix metalloproteinase activity and preserves elastin in emphysematous lungs

Respiratory Research, 2021
Background Elastin degradation has been established as one of the driving factors of emphysema. Elastin-derived peptides (EDPs) are shown to act as a chemoattractant for monocytes.
Vaideesh Parasaram, Xiaoying Wang, Pantrika Krisanarungson, Narendra Vyavahare   +3 more
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Engineering Natural and Recombinant Silks for Sustainable Biodevices

Frontiers in Chemistry, 2022
Silk fibroin (SF) is a structural protein derived from natural silkworm silks. Materials fabricated based on SF usually inherit extraordinary physical and biological properties, including high mechanical strength, toughness, optical transparency ...
Xinchen Shen, Haoyuan Shi, Hongda Wei, Boxuan Wu, Qingyuan Xia, Jingjie Yeo, Wenwen Huang, Wenwen Huang   +7 more
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Review of the Relationship between Reactive Oxygen Species (ROS) and Elastin-Derived Peptides (EDPs)

Applied Sciences, 2021
Reactive oxygen species (ROS) are central elements of a number of physiological processes such as differentiation and intracellular signaling, as well as pathological processes, e.g., inflammation or apoptosis.
Konrad A. Szychowski, Bartosz Skóra
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The construction of elastin-like polypeptides and their applications in drug delivery system and tissue repair

Journal of Nanobiotechnology, 2023
Elastin-like polypeptides (ELPs) are thermally responsive biopolymers derived from natural elastin. These peptides have a low critical solution temperature phase behavior and can be used to prepare stimuli-responsive biomaterials.
Yingshu Guo, Shiwei Liu, Dan Jing, Nianzu Liu, Xiliang Luo   +4 more
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Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension

Acta Medica Bulgarica, 2019
Background and Aims: An important factor in the development of vascular wall lesions is the degradation of the elastic fiber major protein – elastin. Elastin peptides (EDP) derived from this degradation are present in the circulation and are a stimulus ...
Nikolov A., Blazhev A., Tzekova M., Kostov K., Popovski N.   +4 more
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Uncoupling of Elastin Complex Receptor during In Vitro Aging Is Related to Modifications in Its Intrinsic Sialidase Activity and the Subsequent Lactosylceramide Production. [PDF]

PLoS ONE, 2015
Degradation of elastin leads to the production of elastin-derived peptides (EDP), which exhibit several biological effects, such as cell proliferation or protease secretion.
Amandine Scandolera, Fanja Rabenoelina, Carine Chaintreuil, Anthony Rusciani, Pascal Maurice, Sébastien Blaise, Béatrice Romier-Crouzet, Hassan El Btaouri, Laurent Martiny, Laurent Debelle, Laurent Duca   +10 more
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Extracellular Matrix in Heart Disease: Focus on Circulating Collagen Type I and III Derived Peptides as Biomarkers of Myocardial Fibrosis and Their Potential in the Prognosis of Heart Failure: A Concise Review

Metabolites, 2022
Accumulating evidence indicates that two major proteins are responsible for the structural coherence of bounding cardiomyocytes. These biomolecules are known as myocardial fibrillar collagen type I (COL1) and type III (COL3).
Asparuh Nikolov, Nikola Popovski
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TRPM7/RPSA Complex Regulates Pancreatic Cancer Cell Migration

Frontiers in Cell and Developmental Biology, 2020
Pancreatic ductal adenocarcinoma (PDAC) is a malignancy with a very poor prognosis due to highly metastatic profile. Cell migration is an essential step of the metastatic cascade allowing cancer cells to spread toward target tissues.
Thibaut Lefebvre, Pierre Rybarczyk, Pierre Rybarczyk, Clara Bretaudeau, Alison Vanlaeys, Rémi Cousin, Sylvie Brassart-Pasco, Denis Chatelain, Isabelle Dhennin-Duthille, Halima Ouadid-Ahidouch, Bertrand Brassart, Mathieu Gautier   +11 more
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Characterization of novel interactions with membrane NEU1 highlights new regulatory functions for the Elastin Receptor Complex in monocyte interaction with endothelial cells

Cell & Bioscience, 2021
Background Vascular aging is associated with remodeling of elastin, one of the main extracellular matrix component of the arterial wall, and production of elastin-derived peptides (EDP).
Olivier Bocquet, Dignê Tembely, Damien Rioult, Christine Terryn, Béatrice Romier, Amar Bennasroune, Sébastien Blaise, Hervé Sartelet, Laurent Martiny, Laurent Duca, Pascal Maurice   +10 more
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