Results 161 to 170 of about 14,557 (201)

Molecular Targeting of Immunosuppressants Using a Bifunctional Elastin-Like Polypeptide. [PDF]

open access: yesBioconjug Chem, 2019
Ju Y   +7 more
europepmc   +1 more source

Cytokine conjugates to elastin-like polypeptides

Advanced Drug Delivery Reviews, 2022
Cytokines are a group of pleiotropic proteins which are crucial for various biological processes and useful as therapeutics. However, they usually suffer from the poor stability, extreme short circulation half-life, difficulty in high-yield and large-scale production and side effects, which greatly restricts their applications.
Like, Gong   +3 more
openaire   +2 more sources

Alginate/human elastin-like polypeptide composite films with antioxidant properties for potential wound healing application [PDF]

open access: yesInternational Journal of Biological Macromolecules, 2020
In this contribution we describe the preparation and characterization of a series of cross-linked films based on the combination of an elastin-derived biomimetic polypeptide (Human elastin-like polypeptide (HELP)) with alginate (ALG) to obtain a ...
Carlo Bergonzi   +2 more
exaly   +2 more sources

Recombination and Purification of Elastin-Like Polypeptides

2021
Elastin, as an extracellular matrix protein, has inherent advantages for biomedical applications. For example, it is highly extensible and biocompatible, biodegradable, and has no immunogenicity. However, directly extracting elastin from biological tissues remains challenging because they usually coexist with other proteins such as collagen. Therefore,
Chenxi, Zhao   +4 more
openaire   +2 more sources

Genetically Encoded Elastin‐Like Polypeptides for Drug Delivery

Advanced Healthcare Materials, 2021
AbstractElastin‐like polypeptides (ELPs) are thermally responsive biopolymers that consist of a repeated amino acid motif derived from human tropoelastin. These peptides exhibit temperature‐dependent phase behavior that can be harnessed to produce stimuli‐responsive biomaterials, such as nanoparticles or injectable drug delivery depots.
Irene C. Jenkins   +2 more
openaire   +2 more sources

Spectroscopic studies on elastin-like synthetic polypeptides

International Journal of Biological Macromolecules, 1990
Spectroscopic studies on synthetic polypeptides containing the unit-X-G-G (X=V or L) are reported. The sequences, constituting either fragments or model of elastin, were shown to adopt type II beta-turns together with an ensemble of unordered conformations.
M. A. CASTIGLIONE MORELLI   +3 more
openaire   +4 more sources

Epitope tagging for tracking elastin-like polypeptides

Biomaterials, 2006
Elastin-like polypeptides (ELPs) are a class of biocompatible, non-immunogenic and crosslinkable biomaterials that offer promise for use as an injectable scaffold for cartilage repair. In this study, an oligohistidine (His(6)) epitope tag was incorporated at the N-terminus of an ELP using recombinant DNA techniques to permit tracking without ...
Shin R, Ong   +5 more
openaire   +2 more sources

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