Evidence of compensatory elastin remodeling in non-prolapsed uterosacral ligaments and its divergence in histopathological subtypes of pelvic organ prolapse. [PDF]
Orlicky DJ +11 more
europepmc +1 more source
ABSTRACT Introduction The aim was the immunohistological evaluation of a porcine dermal matrix (PDM) in comparison to a non‐augmented control group for peri‐implant tissue thickening. Materials and Methods This human histological study involved the placement of PDM in the test group (20 patients) during implant placement, while the control group ...
F. R. S. Michallek +9 more
wiley +1 more source
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
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Intraoperative biopsy imaging of lung cancer risk. [PDF]
Qian S +14 more
europepmc +1 more source
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Collagen-elastin microstructural network and its mechanical implications in the anterior cruciate ligament: A feasibility study. [PDF]
Cao C +6 more
europepmc +1 more source
Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
Impact of fractional CO<sub>2</sub> laser therapy on vaginal wall histology in breast cancer survivors. [PDF]
Jacobsen S +7 more
europepmc +1 more source
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki +4 more
wiley +1 more source
Case Report: Newly discovered ELN gene mutation in congenital heart disease: case analysis and review. [PDF]
Cheng P, Wang G, Qiu J, Xie X, An Y.
europepmc +1 more source

