Results 21 to 30 of about 113,337 (338)
Spatial and temporal changes in extracellular elastin and laminin distribution during lung alveolar development [PDF]
Lung alveolarization requires precise coordination of cell growth with extracellular matrix (ECM) synthesis and deposition. The role of extracellular matrices in alveogenesis is not fully understood, because prior knowledge is largely extrapolated from ...
Chen, Hui+9 more
core +2 more sources
THE aorta consists of elastin, collagen and a number of other proteins; it also contains about 2 per cent of carbohydrate1. Elastin is usually isolated from aorta or ligamentum nuchae by treatment with acids and alkalis at elevated temperatures; however, a small amount of ill-defined carbohydrate appears to be held strongly and cannot be easily ...
openaire +3 more sources
The mechanical stability, elasticity, inherent bioactivity, and self‐assembly properties of elastin make it a highly attractive candidate for the fabrication of versatile biomaterials. The ability to engineer specific peptide sequences derived from elastin allows the precise control of these physicochemical and organizational characteristics, and ...
Giselle C, Yeo+5 more
openaire +3 more sources
Physiologic compliance in engineered small-diameter arterial constructs based on an elastomeric substrate. [PDF]
Compliance mismatch is a significant challenge to long-term patency in small-diameter bypass grafts because it causes intimal hyperplasia and ultimately graft occlusion.
Abbott+50 more
core +1 more source
Fibulin-4 is essential for maintaining arterial wall integrity in conduit but not muscular arteries [PDF]
Homozygous or compound heterozygous mutations in fibulin-4 (FBLN4) lead to autosomal recessive cutis laxa type 1B (ARCL1B), a multisystem disorder characterized by significant cardiovascular abnormalities, including abnormal elastin assembly, arterial ...
Broekelmann, Thomas J+5 more
core +3 more sources
Elastin peptides display a wide range of biological activities. This study aimed to investigate the ameliorative effect of tuna elastin peptides on adjuvant-induced arthritis (AIA). The daily administration of tuna elastin peptides markedly downregulated
Zhen Zhang+8 more
doaj
Elastin peptides signaling relies on neuraminidase-1-dependent lactosylceramide generation. [PDF]
The sialidase activity of neuraminidase-1 (Neu-1) is responsible for ERK 1/2 pathway activation following binding of elastin peptide on the elastin receptor complex.
Anthony Rusciani+9 more
doaj +1 more source
Elastin Structure, Synthesis, Regulatory Mechanism and Relationship With Cardiovascular Diseases
As the primary component of elastic fibers, elastin plays an important role in maintaining the elasticity and tensile ability of cardiovascular, pulmonary and many other tissues and organs.
Keke Wang+3 more
doaj +1 more source
Changes in the physical structure and chain dynamics of elastin network in homocysteine-cultured arteries [PDF]
The thermal and dielectric properties of the elastin network were investigated in arteries cultured with physiological and pathological concentrations of homocysteine, an aminoacid responsible of histological impairments in human arteries.
Chareyre, Corinne+6 more
core +1 more source
Cardiac extracellular matrices (ECM) play crucial functional roles in cardiac biomechanics. Previous studies have mainly focused on collagen, the major structural ECM in heart wall. The role of elastin in cardiac mechanics, however, is poorly understood.
Xiaodan Shi+15 more
doaj