Results 71 to 80 of about 111,358 (307)

Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

Advanced Healthcare Materials, EarlyView.
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi, Nadia Vertti‐Quintero, Julien Husson, Anne‐Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N. Baroud   +7 more
wiley   +1 more source

Induction of protein body formation in plant leaves by elastin-like polypeptide fusions

BMC Biology, 2009
Background Elastin-like polypeptides are synthetic biopolymers composed of a repeating pentapeptide 'VPGXG' sequence that are valuable for the simple non-chromatographic purification of recombinant proteins.
Joensuu Jussi J, Conley Andrew J, Menassa Rima, Brandle Jim E   +3 more
doaj   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Preparation and Property Analyses of Elastin Peptides from Different Freshwater Fish Sources

Shipin gongye ke-ji
In order to fully utilize freshwater fish resources and develop new sources of elastin peptides, the basic information of the whole heart and bulbus arteriosus of three common bulk freshwater fish was measured in this study, including their mass, total ...
Shunfeng TIAN, Jing SHI, Shuping MA, Mengmeng FENG, Yongkang LUO, Yanfei JIANG, Chunyue ZHAO   +6 more
doaj   +1 more source

Acquired Localized Cutis Laxa due to Increased Elastin Turnover

Case Reports in Dermatology, 2016
Cutis laxa is a rare disease characterized by abnormal skin wrinkling and laxity, due to decreased elastin synthesis or structural extracellular matrix defects.
Rie Harboe Nygaard, Scott Maynard, Peter Schjerling, Michael Kjaer, Klaus Qvortrup, Vilhelm A. Bohr, Lene J. Rasmussen, Gregor B.E. Jemec, Michael Heidenheim   +8 more
doaj   +1 more source

On the tear resistance of skin. [PDF]

, 2015
Tear resistance is of vital importance in the various functions of skin, especially protection from predatorial attack. Here, we mechanistically quantify the extreme tear resistance of skin and identify the underlying structural features, which lead to ...
Gludovatz, Bernd, Meyers, Marc A, Ritchie, Robert O, Schaible, Eric, Sherman, Vincent R, Stewart, Polite, Yang, Wen   +6 more
core   +2 more sources

Coacervates Made of Elastin‐Like Polypeptides Fused with Melanocyte‐Stimulating Hormone and Monocyte Chemoattractant Protein Enhance Skin Wound Healing in Spinal Cord‐Injured Mice

Advanced Healthcare Materials, EarlyView.
Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar, Dhruv Patel, Greeshma Manjunath, Shashank Madhavan, Ashley Mathew, Dnyaneshwari Rananavare, Jahnavi Shah, Francois Berthiaume   +7 more
wiley   +1 more source

Elastin peptides in aging and pathological conditions

Biomolecular Concepts, 2013
Elastin is the protein responsible for the resilience of vertebrate tissue. It is an extremely stable protein deposited during the early stages of life and experiencing almost no renewal. As a consequence, it can be considered that each individual has an
Baud Stéphanie, Duca Laurent, Bochicchio Brigida, Brassart Bertrand, Belloy Nicolas, Pepe Antonietta, Dauchez Manuel, Martiny Laurent, Debelle Laurent   +8 more
doaj   +1 more source

Proteomic analysis of the bovine and human ciliary zonule [PDF]

, 2016
PURPOSE: The zonule of Zinn (ciliary zonule) is a system of fibers that centers the crystalline lens on the optical axis of the eye. Mutations in zonule components underlie syndromic conditions associated with a broad range of ocular pathologies ...
Bassnett, Steven, David, Larry L, De Maria, Alicia, Wilmarth, Phillip A   +3 more
core   +2 more sources

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source