Results 71 to 80 of about 345,892 (194)

Elastin-derived peptides as building-blocks for novel material functionalities

open access: yes, 2015
Elastin-derived peptides are gaining increasing interest as potential biomaterials. Short elastin-derived peptides are able to self-assemble in fibrils as the entire elastin protein.
PEPE, Antonietta   +5 more
core   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi   +6 more
wiley   +1 more source

Intracellular construction of topology-controlled polypeptide nanostructures with diverse biological functions

open access: yesNature Communications, 2017
The intracellular topology of a nanostructure plays a major role in its interactions with the cell and accordingly, its biological applications. Here, the authors design peptides that intracellularly polymerize into elastin-like polypeptides and assemble
Li-Li Li   +6 more
doaj   +1 more source

Self-assemble peptide biomaterials and their biomedical applications

open access: yesBioactive Materials, 2019
Inspired by self-assembling peptides found in native proteins, deliberately designed engineered peptides have shown outstanding biocompatibility, biodegradability, and extracellular matrix-mimicking microenvironments.
Jun Chen, Xuenong Zou
doaj   +1 more source

Engineering an artificial trachea: Quantitative benchmarks and modular strategies for mechanics, epithelialization, and vascular integration

open access: yesFlexMat, EarlyView.
In this work, we first examine the limitations of surgical repair and stenting, including migration, granulation, mucus plugging, and infection. We then translate these failures into engineering constraints involving geometry, mechanics, fixation, degradation, junctional stress, and remodeling.
Yiwei Xu   +6 more
wiley   +1 more source

Collagen peptides affect collagen synthesis and the expression of collagen, elastin, and versican genes in cultured human dermal fibroblasts

open access: yesFrontiers in Medicine
BackgroundCollagen is one of the major proteins of the skin and it is particularly important for its strength and resilience. Skin aging is a natural process that is characterized by the decrease and fragmentation of collagen in the dermis.
Stephan Dierckx   +6 more
doaj   +1 more source

Molecular Characterization of Elastic Deformation in Elastin Mimetic Peptide [LGGVG]3

open access: yesMedžiagotyra, 2018
Owing to the dramatic elasticity of elastin mimetic peptides, attention is accumulating to the molecular properties of the elastic polymers. This work reports on the molecular characterization of elastic deformation in an elastin mimetic peptide [LGGVG]3
Cheng SUN
doaj   +1 more source

Chemical and conformational changes in proteins through clean label strategies for enhanced functionality: Recent advances

open access: yesFood Biomacromolecules, EarlyView.
Abstract Process‐based functionalization of food materials has gained immense interest as they contribute to the development of clean label ingredients that can offer similar functional properties as food additives of synthetic origin. Chemical and conformational changes in proteins can induce diverse and targeted functionalities that can be useful as ...
Bindvi Arora   +7 more
wiley   +1 more source

Bioactive Peptides: Applications and Relevance for Cosmeceuticals

open access: yesCosmetics, 2018
Peptides found in skin can act by different mechanisms of action, being able to function as epidermal or nervous growth factors or even as neurotransmitters.
Tamyres Nassa Lima   +1 more
doaj   +1 more source

Ameliorative Effects of Peptides from the Oyster (Crassostrea hongkongensis) Protein Hydrolysates against UVB-Induced Skin Photodamage in Mice

open access: yesMarine Drugs, 2020
Chronic exposure to ultraviolet B (UVB) irradiation is a major cause for skin photoaging. UVB induces damage to skin mainly by oxidative stress, inflammation, and collagen degradation. This paper investigated the photo-protective effects of peptides from
Zhilan Peng   +6 more
doaj   +1 more source

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