Results 81 to 90 of about 795 (185)

Relationship between Hypercalcemia and Renal Function with Eldecalcitol

YAKUGAKU ZASSHI
Eldecalcitol (ELD), an active vitamin D3 analog, is extensively prescribed in Japan for the treatment of osteoporosis. However, hypercalcemia remains a significant concern, particularly in patients with impaired renal function. Data on the extent to which renal dysfunction increases the risk of hypercalcemia are limited.
Shinji, Oda, Takayuki, Miyoshi, Kenichi, Furuta, Kenshi, Takechi, Takashi, Otsuka   +4 more
openaire   +2 more sources

Liver stiffness as a cornerstone in heart disease risk assessment

Liver International, Volume 44, Issue 2, Page 344-356, February 2024.
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) typically presents with hepatic fibrosis in advanced disease, resulting in increased liver stiffness. A subset of patients further develops liver cirrhosis and hepatocellular carcinoma.
Joost Boeckmans, Laurent Sandrin, Christian Knackstedt, Jörn M. Schattenberg   +3 more
wiley   +1 more source

Treatment with eldecalcitol positively affects mineralization, microdamage, and collagen crosslinks in primate bone [PDF]

, 2015
Eldecalcitol (ELD), an active form of vitamin D analog approved for the treatment of osteoporosis in Japan, increases lumbar spine bone mineral density (BMD), suppresses bone turnover markers, and reduces fracture risk in patients with osteoporosis.We ...
Amizuka, N., Hasegawa, T., Saito H., Burr, DB., Grynpas, MD., Allen, MR., Kida, Y., Smith, SY., Marumo, K., Saito, M., Doyle, N.   +10 more
core   +1 more source

Eldecalcitol (ED-71)-induced exosomal miR-6887-5p suppresses squamous cell carcinoma cell growth by targeting heparin-binding protein 17/fibroblast growth factor–binding protein-1 (HBp17/FGFBP-1) [PDF]

, 2020
Heparin-binding protein 17/fibroblast growth factor–binding protein-1 (HBp17/FGFBP-1) was purified from A431 cell-conditioned media based on its capacity to bind to fibroblast growth factor 1 and 2 (FGF-1 and FGF-2).
Rosli, S. N. Z., Hamada, A., Okamoto, T., Shintani, T., Higaki, M.   +4 more
core   +1 more source

Zinc improves Denosumab and eldecalcitol efficacy for bone mineral density in patients with hypozincemia

Introduction We aimed to investigate the effects of zinc deficiency and zinc medication in osteoporosis patients undergoing denosumab (DMAb). Materials and methods This retrospective study was conducted at a single hospital.
Kanayama, Masahiro, Shimizu, Tomohiro, Oha, Fumihiro, Ishizu, Hotaka, Ohashi, Yusuke, Iwasaki, Norimasa, Kusunoki, Kenichi   +6 more
core   +1 more source

Effect of eldecalcitol, an active vitamin D analog, on hip structure and biomechanical properties: 3D assessment by clinical CT. [PDF]

, 2011
The effects of an active vitamin D analog, eldecalcitol (ELD), on bone mineral density (BMD), bone geometry, and biomechanical properties of the proximal femur were investigated by using clinical CT.
Masako Ito, Toshitaka Nakamura, Shiraki, Masataka, Nakamura, Toshitaka, Masao Fukunaga, Masataka Shiraki, Fukunaga, Masao, Matsumoto, Toshio, Ito, Masako, Toshio Matsumoto   +9 more
core   +1 more source

Changes in bone density and metabolism marker levels in type I Gaucher's disease following annual zoledronic acid hydrate administration: A case report

Bone Reports
We present a rare case of type I GD with frequent bone complications. After multiple fractures the patient received 5 mg zoledronic acid hydrate, which improved TRACP-5b and P1NP levels.
Hiroyuki Onuma, Naoki Haraguchi
doaj   +1 more source

Detailed data of the study participants.

, 2023
Age, age at the DXA scan; FR, the number of fractures up to the DXA scan divided by the age; BMDHAZ, height-for-age Z-score-adjusted bone mineral density-for-age Z-score; BMAD, Z-score of bone mineral apparent density; TBS, Z-score of trabecular bone ...
Takeshi Ishimi (16898669), Makoto Fujiwara (312588), Yasuhisa Ohata (312589), Taichi Kitaoka (312591), Shinji Takeyari (16898678), Hirofumi Nakayama (14870363), Yukako Nakano (16898675), Keiichi Ozono (312596), Kenichi Yamamoto (9757886), Chieko Yamada (16898672), Takuo Kubota (312592)   +10 more
core   +1 more source

Long-term Observation of Osteomalacia Caused by Adefovir-Induced Fanconi’s Syndrome [PDF]

, 2014
A 64-year-old man suffering polyarthralgia and bone pain was referred to our hospital. Renal dysfunction, hypophosphatemia and increased levels of bone alkaline phosphatase were found.
Hanayama, Yoshihisa, Waseda, Koichi, Ebara, Hirotaka, Otsuka, Fumio, Terasaka, Tomohiro, Hidan, Ko, Kawabata, Tomoko, Ueta, Eijiro, Takaki, Akinobu, Sugiyama, Hitoshi   +9 more
core   +1 more source

A Health Technology Assessment Based on Chinese Guideline: Active Vitamin D and Its Analogs in the Treatment of Osteoporosis

Drug Design, Development and Therapy
Siyong Huang, Jiabao Li, Xiao Hu, Jisheng Chen Key Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, People’s Republic of ChinaCorrespondence: Jisheng Chen, Key Specialty of Clinical Pharmacy,
Huang S, Li J, Hu X, Chen J
doaj