Results 91 to 100 of about 1,034,727 (322)
Molecular Oncology, EarlyView.The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina +17 more
wiley +1 more source
Molecular Oncology, EarlyView.We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić +31 more
wiley +1 more source
The Roles of Familiarity Design in Active Ageing [PDF]
arXiv, 2016 The elderly often struggle when interacting with technologies. This is because the software and hardware components of the technologies are not familiar to the elderly's mental model. This is a lack of empirical studies about how the concept of familiarity can be infused into the design of interactive technology systems to bridge the digital divide ...
arxiv
Molecular Oncology, EarlyView.Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale +9 more
wiley +1 more source
Journal of Orthopaedic Surgery and ResearchAims This study aims to investigate the impacts of failure of pelvic compensation (FPC), as determined by variations in spinopelvic alignment during the transition from the supine to the upright position, on surgical outcomes in patients with adult ...
Dongfan Wang +6 more
doaj +1 more source
Is Everything Fine, Grandma? Acoustic and Linguistic Modeling for Robust Elderly Speech Emotion Recognition [PDF]
arXiv, 2020 Acoustic and linguistic analysis for elderly emotion recognition is an under-studied and challenging research direction, but essential for the creation of digital assistants for the elderly, as well as unobtrusive telemonitoring of elderly in their residences for mental healthcare purposes.
arxiv
BMJ, 1973 Anaemia is always pathological and the clinical impression of its presence or absence often erroneous; it is not a con comitant of ageing. The reported incidence has varied greatly. Pincherle and Shanks1 found it in only 0*42% of 2,000 busi ness executives, 300 of whom were over 60 years.
openaire +3 more sources
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
BMC SurgeryObjective Failure to understand long-term quality of life and functional outcomes hinders effective decision making and prognostication. Therefore, the study aims to predict and analyse the unfavorable outcomes (FOs) in elderly patients undergoing lumbar
Peng Cui +6 more
doaj +1 more source
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
Molecular Oncology, EarlyView.In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang +8 more
wiley +1 more source