Results 91 to 100 of about 1,056,966 (297)

The role of supine imaging in assessing failure of pelvic compensation and its impact on surgical outcomes in patients with adult spinal deformity

Journal of Orthopaedic Surgery and Research
Aims This study aims to investigate the impacts of failure of pelvic compensation (FPC), as determined by variations in spinopelvic alignment during the transition from the supine to the upright position, on surgical outcomes in patients with adult ...
Dongfan Wang, Wei Wang, Yu Wang, Chao Kong, Shuaikang Wang, Xiaolong Chen, Shibao Lu   +6 more
doaj   +1 more source

Reducing inappropriate psychotropic drug use in nursing home residents with dementia: protocol for participatory action research in a stepped-wedge cluster randomized trial

BMC Psychiatry, 2019
Background Psychotropic drugs are often prescribed to treat neuropsychiatric symptoms in nursing home residents with dementia, despite having limited efficacy and considerable side effects.
Claudia M. Groot Kormelinck, Charlotte F. van Teunenbroek, Boudewijn J. Kollen, Margreet Reitsma, Debby L. Gerritsen, Martin Smalbrugge, Sytse U. Zuidema   +6 more
doaj   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Advancing the timing of drainage removal: a comprehensive analysis of different drainage removal criteria in patients undergoing short-level lumbar fusion surgery

BMC Surgery
Objective To specifically evaluate the safety and benefit of different drainage removal criteria (50 ml and 100 ml per 24 h) in patients undergoing short-level lumbar fusion surgery.
Peng Cui, Di Han, Xiao-Long Chen, Peng Wang, Shi-Bao Lu   +4 more
doaj   +1 more source

Care of the Elderly in General Practice [PDF]

, 1957
Jennifer Fry
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

How Chronic is Pulmonary Tuberculosis in the Elderly? [PDF]

, 1959
J. Smith
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

The impact of probiotics on glycemic control during the first 3 months after sleeve gastrectomy: a prospective placebo‑controlled study

Videosurgery and Other Miniinvasive Techniques
Introduction: Sleeve gastrectomy (SG) is a safe metabolic and bariatric surgery but it often leads to postoperative gastrointestinal issues, such as constipation and bloating. The use of probiotics after SG seems to alleviate these symptoms.
Natalia Mazek, Julia Młyńska, Ewelina Sosnowska-Turek, Paweł Lech, Natalia Dowgiałło-Gornowicz   +4 more
doaj   +1 more source

Haemoglobin Levels in a Group of Elderly Persons Living at Home Alone or with Spouse [PDF]

, 1953
W. Hobson, E. K. Blackburn
openalex   +1 more source