Results 101 to 110 of about 1,374,958 (308)
Bearing fruit: a programme for primary schools about being young and growing old.
, 1993 1993, the European Year of Older People and Solidarity between Generations is, I believe, an important initiative in increasing awareness and understanding between the younger and older generations of our society.
Dempsey, Anne
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
, 1999 Vinorelbine, a semisynthetic vinca alkaloid, represents a welltolerated treatment for elderly patients with advanced non-small-cell lung cancer (NSCLC).
GRIDELLI C +3 more
core +1 more source
Journal of Orthopaedic Surgery and ResearchAims This study aims to investigate the impacts of failure of pelvic compensation (FPC), as determined by variations in spinopelvic alignment during the transition from the supine to the upright position, on surgical outcomes in patients with adult ...
Dongfan Wang +6 more
doaj +1 more source
Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 1989 Longitudinal Cohort Study: Electrocardiogram and blood pressure were taken biannually along with history taking, physical examination and other laboratory studies. 6,690 subjects were included in this study in whom at least 7 out of 9 biannual check up examinations were performed.
openaire +3 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
The economics and financing of long term care of the elderly in Ireland.
, 1994 The importance of addressing the issues relating to the economics and financing of long-term care for older people in Ireland cannot be over emphasised.
Hughes, Jenny, O'Shea, Eamon
core