Results 121 to 130 of about 1,374,958 (308)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Why Don't the Elderly Live With Their Children? A New Look [PDF]

Perhaps no single statistic raises more concern about post War changes in the U.S. family than the proportion of the elderly living alone. Since 1940 the proportion of elderly living alone and in institutions has risen dramatically.
John Morris, Laurence J. Kotlikoff
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Advancing the timing of drainage removal: a comprehensive analysis of different drainage removal criteria in patients undergoing short-level lumbar fusion surgery

BMC Surgery
Objective To specifically evaluate the safety and benefit of different drainage removal criteria (50 ml and 100 ml per 24 h) in patients undergoing short-level lumbar fusion surgery.
Peng Cui, Di Han, Xiao-Long Chen, Peng Wang, Shi-Bao Lu   +4 more
doaj   +1 more source

The impact of probiotics on glycemic control during the first 3 months after sleeve gastrectomy: a prospective placebo‑controlled study

Videosurgery and Other Miniinvasive Techniques
Introduction: Sleeve gastrectomy (SG) is a safe metabolic and bariatric surgery but it often leads to postoperative gastrointestinal issues, such as constipation and bloating. The use of probiotics after SG seems to alleviate these symptoms.
Natalia Mazek, Julia Młyńska, Ewelina Sosnowska-Turek, Paweł Lech, Natalia Dowgiałło-Gornowicz   +4 more
doaj   +1 more source

Determinants of Elderly Poverty in Vietnam [PDF]

By using household data in 2004, this paper identifies the determinants of the elderly poverty in Vietnam. We find that urban and rural elderly are substantially different, and thus they should be analyzed separately.
Pfau, Wade Donald, Giang, Thanh Long
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

A Novel Theoretical Hypothesis on Comorbidity in the Elderly—The Disease of Sympathetic Overdrive (DSO)

Aging Medicine
The coexistence of multimorbidity and geriatric syndromes is a big character and role target to manage for the clinic works in older age, but related theories still require innovation and exploration.
Li Jie, Kong Jian, Yu Boxin, Li Hongyang
doaj   +1 more source

Use of Medicines by Community Dwelling Elderly in Ontario [PDF]

OBJECTIVE: Prescription medicine use by the elderly is of growing concern as indicated by a large literature focused on rising costs, patient compliance and the appropriateness of use.
Peri J. Ballantyne, Joan A. Marshman, Philippa J. Clarke, J. Charles Victor   +3 more
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source