Results 101 to 110 of about 3,308,023 (394)

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

The Effect of Melilotous Officinalis Oil on the Physical Function of Older Adults With Mild to Moderate Knee Osteoarthritis: A Double-Blind Randomized Controlled Trial

open access: yesSālmand, 2019
Objectives: Osteoarthritis (OA) is one of the most common diseases among older people that although does not directly lead to mortality, is one the leading causes of disability in older people.
Gholamreza Ansari   +6 more
doaj  

[Review of the book \u3ci\u3eRetirement Income Opportunities in an Aging America: Income Levels and Adequacy\u3c/i\u3e] [PDF]

open access: yes, 1983
[Excerpt] The slant of this volume will not appeal to everyone. Consider the following: During the last twenty years, the elderly\u27s financial status has improved substantially. Today those who are over age 65 receive income from more sources and have
Fields, Gary S
core   +1 more source

Insomnia in the Elderly: A Review.

open access: yesJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018
BACKGROUND Insomnia remains one of the most common sleep disorders encountered in the geriatric clinic population, frequently characterized by the subjective complaint of difficulty falling or maintaining sleep, or nonrestorative sleep, producing ...
Dhaval Patel   +2 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Hypertension in the elderly

open access: yesTurk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology, 2017
Hypertension (HT) is a common problem in elderly persons (age >65 years), reaching a prevalence as high as 60 to 80%. Isolated systolic HT mostly occurs in older patients. Treatment of HT in all patients, independent of age, consists of lifestyle modifications and antihypertensive therapy.
openaire   +4 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Age-dependent differences in human brain activity using a face- and location-matching task: An fMRI study [PDF]

open access: yes, 2007
Purpose: To evaluate the differences of cortical activation patterns in young and elderly healthy subjects for object and spatial visual processing using a face- and location-matching task.
Bokde, A. L. W.   +9 more
core   +1 more source

The Effect of Information Communication Technology Interventions on Reducing Social Isolation in the Elderly: A Systematic Review

open access: yesJournal of Medical Internet Research, 2016
Background The aging of the population is an inexorable change that challenges governments and societies in every developed country. Based on clinical and empirical data, social isolation is found to be prevalent among elderly people, and it has negative
Yi-Ru Regina Chen, P. Schulz
semanticscholar   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

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