Results 111 to 120 of about 3,263,574 (391)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Latent segmentation of older adults in the use of social networks and e-banking services [PDF]

open access: yes, 2019
Introduction. This study analyses heterogeneity in the online behaviour of elderly people. Previous research has centred on the socio-demographic segmentation of the elderly regarding their Internet use. Method.
Arenas Gaitán, Jorge   +2 more
core  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Population Aging, Elderly Migration and Education Spending: Intergenerational Conflict Revisited [PDF]

open access: yes
Elderly have been increasingly targeted as a group to enhance economic development and the tax base in communities. While recent literature on elderly migration tends to focus on how elderly migration patterns are influenced by state fiscal variables ...
Tosun, Mehmet S.   +2 more
core   +3 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Dynamic Changes in ALFF and DC in Subthreshold Depression Before and After ICBT Intervention

open access: yesNeuropsychiatric Disease and Treatment
Yu Wang,1,* Yuchen Ying,2,* Zili Zhu,1 Li Wang,2 YiLing Yang,2 Li Zhang,2 Wenquan Yu,1 Yichuan Liang,1 Hui Zhang,1 Yunxin Ji,3 Yuning Pan1 1Department of Radiology, THE First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang ...
Wang Y   +10 more
doaj  

Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications.

open access: yesEndocrine reviews, 2001
Vitamin D deficiency is common in the elderly, especially in the housebound and in geriatric patients. The establishment of strict diagnostic criteria is hampered by differences in assay methods for 25-hydroxyvitamin D. The synthesis of vitamin D3 in the
P. Lips
semanticscholar   +1 more source

Epilepsy in the Elderly

open access: yesInternational Journal of Gerontology, 2012
SummaryElderly people are the largest and continuously fastest growing population among patients with epilepsy. Elderly patients with epilepsy are very different from other age groups in many respects and clinicians shouldn’t treat them in the same way as younger adults.
Lu-An Chen   +2 more
openaire   +2 more sources

Food for talk: photo frames to support social connectedness for elderly people in a nursing home [PDF]

open access: yes, 2009
Social connectedness is crucial to someone’s well-being. A case study is conducted to test whether the social connectedness of elderly people living in a nursing home and their family and friends can be improved through a photo frame.
Biemans, Margit, Dijk, Betsy van
core   +4 more sources

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