Results 81 to 90 of about 3,308,023 (394)
A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly
Aging and Disease, 2018 NSAIDs, non-steroidal anti-inflammatory drugs, are one of the most commonly prescribed pain medications. It is a highly effective drug class for pain and inflammation; however, NSAIDs are known for multiple adverse effects, including gastrointestinal ...
Supakanya Wongrakpanich +3 more
semanticscholar +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Ceaseless Toil? Health and Labor Supply of the Elderly in Rural China [PDF]
, 2003 Deborah Davis-Friedmann (1991) described the “retirement” pattern of the Chinese elderly in the prereform era as “ceaseless toil”: lacking sufficient means of support, the elderly had to work their entire lives.
Benjamin, Dwayne +2 more
core +2 more sources
Balance and gait in the elderly: A contemporary review
Laryngoscope Investigative Otolaryngology, 2019 The prevalence of balance and gait deficits increases with age and is associated with the increased incidence of falls seen in the elderly population; these falls are associated with significant morbidity and mortality.
Muyinat Y Osoba +3 more
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Stem Cell Research & TherapyBackground Fine particulate matter (PM2.5) exposure significantly exacerbates respiratory morbidity, particularly in asthmatic individuals, highlighting an urgent need for effective therapeutic interventions.
Jianling Liu +9 more
doaj +1 more source
Stroke in the Setting of Giant Cell Arteritis: A Case Report
Case Reports in Medicine, 2010 We describe an unusual complication of a common disease: stroke presenting in a man recently diagnosed with polymyalgia rheumatica. Initial inflammatory markers were misleading. We discuss pitfalls in diagnosis, and approach to management.
S. McDermott +3 more
doaj +1 more source
Geographic Breakdown of Georgia's Interstate Migration Patterns - Brief [PDF]
, 2006 This brief looks at the geographic breakdown of Georgia's interstate migration patterns for both the elderly and non-elderly.
Jon Rork
core
Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly
New England Journal of Medicine, 2018 BACKGROUND Aspirin is a well‐established therapy for the secondary prevention of cardiovascular events. However, its role in the primary prevention of cardiovascular disease is unclear, especially in older persons, who have an increased risk.
J. McNeil +32 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source