Results 81 to 90 of about 3,202,647 (392)

Effectiveness and costs of a new framework for selecting absorbent urinary incontinence products compared with current practice: a cohort study

open access: yesBMJ Open, 2022
Objectives To improve continence care in the Netherlands, a new framework has been developed in which a shift has been made from incontinence severity as the sole criterion for selecting incontinence products to a focus on patient need for daily life ...
Michiel R de Boer   +8 more
doaj   +1 more source

Elderly health, wealth and coresidence with adult children in rural India [PDF]

open access: yes, 2006
Little is known about the living conditions of a growing number of elderly in India who predominantly coreside with their children. Mutual sharing of responsibilities is important in coresidency arrangements involving exchange of financial and other ...
Pal, S
core  

Housing the Aging Baby Boomers: Implications for Local Policy [PDF]

open access: yes, 2008
Most elderly want to age in place. Yet, most elderly live in suburban and rural communities ill-suited to meet the changing aging-related demands. This paper discusses various issues communities need to address when balancing the demands of aging baby ...
Geoffrey K. Turnbull, John W. Matthews
core   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Human dental pulp stem cells attenuate airway inflammation in mice with PM2.5-induced asthma exacerbation by inhibiting the pyroptosis pathway

open access: yesStem Cell Research & Therapy
Background Fine particulate matter (PM2.5) exposure significantly exacerbates respiratory morbidity, particularly in asthmatic individuals, highlighting an urgent need for effective therapeutic interventions.
Jianling Liu   +9 more
doaj   +1 more source

An intervention to support stroke survivors and their carers in the longer term (LoTS2Care): study protocol for the process evaluation of a cluster randomised controlled feasibility trial

open access: yesTrials, 2018
Background Whilst pathways relating to the early stages of stroke care have become well established, strategies for longer-term care are less developed and longer-term outcomes remain poor for many stroke survivors. New Start, a complex intervention that
Natasha K. Hardicre   +11 more
doaj   +1 more source

How do elderly pedestrians perceive hazards in the street? - An initial investigation towards development of a pedestrian simulation that incorporates reaction of various pedestrians to environments [PDF]

open access: yes, 2007
In order to evaluate the accessibility of street and transport environments, such as railway stations, we are now developing a pedestrian simulation that incorporates elderly and disable pedestrians and their interaction with various environments ...
Boampong, D   +3 more
core  

Diabetes in the elderly

open access: yesMenopausal Review, 2017
The prevalence of both type 2 diabetes and prediabetes increases with advancing age. The most important factors leading to hyperglycaemia are as follows: deficiency of insulin secretion developing with age, and growing insulin resistance caused by a change in body composition and sarcopaenia.
Katarzyna Mordarska   +1 more
openaire   +4 more sources

Balance and gait in the elderly: A contemporary review

open access: yesLaryngoscope Investigative Otolaryngology, 2019
The prevalence of balance and gait deficits increases with age and is associated with the increased incidence of falls seen in the elderly population; these falls are associated with significant morbidity and mortality.
Muyinat Y Osoba   +3 more
semanticscholar   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

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