Results 31 to 40 of about 305 (128)

Pulsed Electric Field Processing Enhances the Endothelial Bioefficacy of Red Beet (Beta vulgaris L.) Extracts by Restoring Endothelial Nitric Oxide Synthase–Nitric Oxide Signaling in High‐Fat Diet Rats

open access: yeseFood, Volume 7, Issue 4, August 2026.
Pulsed electric field (PEF) processing qualitatively reshapes the phytochemical profile of red beet extracts, resulting in enhanced endothelial bioefficacy. Compared with conventional extraction, PEF‐treated extracts more effectively restore nitric oxide signaling, suppress endothelial inflammation, and normalize vascular structure in high‐fat diet ...
Eunju Jang   +8 more
wiley   +1 more source

Diatoms–copepods: An evolutionary arms race

open access: yesLimnology and Oceanography, Volume 71, Issue 4, April 2026.
Abstract Diatoms and copepods are dominating and diverse groups of phytoplankton and zooplankton, respectively. Diatoms account for 25–40% of ocean primary production, and their main predators, copepods, are arguably the most abundant group of metazoans in the ocean, typically accounting for ~ 80% of zooplankton biomass.
Thomas Kiørboe, Fredrik Ryderheim
wiley   +1 more source

Update on Medical Treatments for Essential Tremor: An International Parkinson and Movement Disorder Society Evidence‐Based Medicine Review

open access: yesMovement Disorders, Volume 41, Issue 4, Page 815-825, April 2026.
Abstract Background The first International Parkinson and Movement Disorder Society Evidence‐Based Medicine (MDS‐EBM) review for essential tremor (ET) was published in 2019; since then, the modified Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology was adopted by MDS, and new evidence exists.
Deepa Dash   +12 more
wiley   +1 more source

The Sirens of Elea: Rationalism, Monism and Idealism in Spinoza [PDF]

open access: yes, 2013
Abstract Michael Della Rocca’s 2008 Spinoza book is a bold, ingenious, and artfully written work. It is—at least to my taste—philosophy at its best. The main thesis of Della Rocca’s book is that at the very center of Spinoza’s philosophy stands the Principle of Sufficient Reason (PSR): the stipulation that everything must be ...
openaire   +1 more source

Distinction and mutual Influences between Parkinson's Disease‐related and unrelated Chronic Pain

open access: yesMovement Disorders Clinical Practice, Volume 13, Issue 2, Page 464-474, February 2026.
Abstract Background Chronic pain (i.e. > 3 months) is a common nonmotor symptom in patients with Parkinson's disease (PD), but the attribution to PD is critical for further treatment. Objectives We explored the PD Pain Classification System (PD‐PCS) criteria for the diagnosis of PD‐related pain and mutual influences between PD‐related and PD‐unrelated ...
Jonathan Hunger   +11 more
wiley   +1 more source

Crystal structure of Schistosoma mansoni cathepsin D1 in complex with a nanobody reveals the conformation of the propeptide‐bound state

open access: yesActa Crystallographica Section D, Volume 82, Issue 2, Page 140-150, February 2026.
Structural characterization of S. mansoni cathepsin D1 in complex with a nanobody reveals the conformation of the propeptide‐bound state and identifies a schistosome‐specific epitope.Schistosoma mansoni cathepsin D1 (SmCD1) has been shown to be an essential enzyme for helminth metabolism due to its role in haemoglobin degradation: a key amino‐acid ...
Kelly L. Parker   +7 more
wiley   +1 more source

Optimisation of a Murine Infection Model With Trichophyton mentagrophytes for Studying the Pathogenesis of Dermatophytosis

open access: yesMycoses, Volume 68, Issue 12, December 2025.
ABSTRACT Background Dermatophytes are the most common agents of superficial mycoses in humans and animals. In a model of Trichophyton benhamiae dermatophytosis in its natural host (guinea pig), the most overexpressed gene was subtilisin 6 (SUB6).
Wilfried Poirier   +10 more
wiley   +1 more source

Natural Products from Mexican Medicinal Plants as Promising Trypanocidal Drugs

open access: yesChemistrySelect, Volume 10, Issue 37, October 6, 2025.
Chagas disease (American Trypanosomiasis) is caused by the protozoan Trypanosoma cruzi. Worldwide it is one of the seventeen neglected tropical diseases. There is a need of new drugs. This review assesses the literature (2012‐2024) of secondary metabolites isolated from Mexican plants active against this parasite.
Karla Daniela Rodríguez‐Hernández   +2 more
wiley   +1 more source

Racotumomab: An Anti-Idiotype Vaccine Related to N-Glycolyl-Containing-Gangliosides. Preclinical and Clinical Data.

open access: yesFrontiers in Oncology, 2012
Neu-glycolyl (NeuGc) containing gangliosides are attractive targets for immunotherapy with anti-idiotype mAbs, because these glycolipids are not normal components of the cytoplasmatic membrane in humans, but their expression has been demonstrated in ...
Ana María eVázquez   +7 more
doaj   +1 more source

The Role of Emotion in Psychosis Onset and Symptom Persistence: A Systematic Review

open access: yesEarly Intervention in Psychiatry, Volume 19, Issue 10, October 2025.
ABSTRACT Aim Emotions have repeatedly been implicated in the development and maintenance of psychosis. However, there is no universally acknowledged theory to account for how emotions influence psychosis. This review, therefore, aims to explore how emotions and emotional coping strategies contribute to the onset and persistence of psychosis symptoms ...
R. Gurnani, A. Georgiades
wiley   +1 more source

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