Results 41 to 50 of about 8,686,837 (274)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Optimization of soot deposition by high-temperature prepolarization of a resistive particulate matter sensor [PDF]
, 2020 For the purposes of the onboard diagnosis (OBD) of diesel particulate filters (DPFs) in diesel exhaust treatment systems, a particulate matter (PM) sensor is applied downstream from the DPFs to detect small amounts of diesel soot that passed through the ...
Fritze, Holger +2 more
core +1 more source
A DC electric field sensor based on optical waveguide-based field mill
AIP AdvancesBased on the Pockels effect of the lithium niobate crystal, an optical field mill DC electric field sensor has been developed. The structural parameters of the rotating shield electrode are optimized by using the COMSOL Multiphysics simulation software ...
Wei Song +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Response Analysis of Electro-Optic Electric Field Sensor
Tikrit Journal of Engineering Sciences, 2009 In this paper an electric field sensor based on the electro-optical effect in Lithium Niobate crystal is studied. The electro-optically induced polarization modification in crystal has been described and the response analyzed for different crystal ...
Dawood N. Saleh
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Sensors, 2019 A novel fiber-optic sensor based on the alternating electric field force actions on polyimide tubing with space charge for power-frequency electric field sensing is presented.
Lutang Wang, Nian Fang
doaj +1 more source
High Voltage, 2022 Electro‐optic electric field sensors based on LiNbO3 are widely used for the measurement of electric fields or transient voltages. However, the working bias of the sensor is influenced by the temperature due to the thermo‐optic effect of LiNbO3.
She Wang +4 more
doaj +1 more source
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source