Results 31 to 40 of about 32,011 (109)

The Functional and Imaging Implications of Left Bundle Branch Pacing in Ischemic Cardiomyopathy

open access: yesBiomolecules
Heart failure with reduced ejection fraction due to ischemic cardiomyopathy remains a significant clinical challenge. Electrical conduction delays exacerbate symptoms by causing uncoordinated contractions, reducing pumping efficiency, and increasing ...
Fulvio Cacciapuoti   +9 more
doaj   +1 more source

Remodeling of Cardiac Gap Junctional Cell–Cell Coupling

open access: yesCells, 2021
The heart works as a functional syncytium, which is realized via cell-cell coupling maintained by gap junction channels. These channels connect two adjacent cells, so that action potentials can be transferred.
Stefan Dhein, Aida Salameh
doaj   +1 more source

Inherited and Acquired Rhythm Disturbances in Sick Sinus Syndrome, Brugada Syndrome, and Atrial Fibrillation: Lessons from Preclinical Modeling

open access: yesCells, 2021
Rhythm disturbances are life-threatening cardiovascular diseases, accounting for many deaths annually worldwide. Abnormal electrical activity might arise in a structurally normal heart in response to specific triggers or as a consequence of cardiac ...
Laura Iop   +3 more
doaj   +1 more source

High resolution 3-Dimensional imaging of the human cardiac conduction system from microanatomy to mathematical modeling

open access: yesScientific Reports, 2017
Cardiac arrhythmias and conduction disturbances are accompanied by structural remodelling of the specialised cardiomyocytes known collectively as the cardiac conduction system.
Robert S. Stephenson   +11 more
doaj   +1 more source

EXAMINATION OF ELECTROPHYSIOLOGICAL PARAMETERS OF THE ATRIUMS IN PATIENTS WITH LONG-TERM PERSISTENT FORM OF ATRIAL FIBRILLATION AND VALVULAR HEART DISEASE

open access: yesKlinicist, 2017
The study objective is to examine electrophysiological parameters of atrial myocardium, characteristics of atrioventricular conduction, and potential factors affecting recurrent atrial fibrillation (AF) in patients with persistent and long-term ...
A. A. Kulikov, L. A. Bokeriya
doaj   +1 more source

The roles of long noncoding RNAs in atrial fibrillation

open access: yesNon-coding RNA Research, 2023
Atrial fibrillation (AF) is a common cardiac arrhythmia that often occurs in patients with structural heart disease and is a significant cause of morbidity and mortality in clinical settings.
Ozal Beylerli   +7 more
doaj   +1 more source

Cardiac Development: A Glimpse on Its Translational Contributions

open access: yesHearts, 2021
Cardiac development is a complex developmental process that is initiated soon after gastrulation, as two sets of precardiac mesodermal precursors are symmetrically located and subsequently fused at the embryonic midline forming the cardiac straight tube.
Diego Franco   +4 more
doaj   +1 more source

Diabetes and Arrhythmias: Pathophysiology, Mechanisms and Therapeutic Outcomes

open access: yesFrontiers in Physiology, 2018
The prevalence of diabetes is rapidly increasing and closely associated with cardiovascular morbidity and mortality. While the major cardiovascular complication associated with diabetes is coronary artery disease, it is becoming increasingly apparent ...
Laurel A. Grisanti
doaj   +1 more source

A human in vitro platform for the evaluation of pharmacology strategies in cardiac ischemia

open access: yesAPL Bioengineering, 2019
Cardiac ischemic events increase the risk for arrhythmia, heart attack, heart failure, and death and are the leading mortality condition globally. Reperfusion therapy is the first line of treatment for this condition, and although it significantly ...
Carlota Oleaga   +7 more
doaj   +1 more source

Intracardiac electrophysiological conduction parameters in adult dogs

open access: yesVeterinary Quarterly, 2017
Background: Invasive electrophysiology study (EPS) is one of the most important adjunct tests for the evaluation of arrhythmias in human medicine. However, EPS is neither well known nor widely used in veterinary medicine.
Alicja Cepiel   +4 more
doaj   +1 more source

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