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Treatment of metastatic melanoma with electrochemotherapy
Journal of Surgical Oncology, 2013Superficially metastatic melanoma still represents a challenging situation for oncologists and a distressing condition for patients. In this circumstance, local treatment by electrochemotherapy, that is, the combination of brief permeabilizing electric pulses with a low‐toxicity anticancer drug, can be a valuable treatment option in selected patients ...
Luca G, Campana +3 more
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Novel electrode designs for electrochemotherapy
Biochimica et Biophysica Acta (BBA) - General Subjects, 1997Direct current pulses for electrochemotherapy treatment are typically administered using two parallel plate electrodes that are placed on either side of the tumor. This simple design has produced high response rates (70 to 85%) in animal studies and in clinical trials. However, parallel plate electrodes are not suitable for all situations.
R A, Gilbert, M J, Jaroszeski, R, Heller
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[Anaesthesia in Electrochemotherapy].
Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2020Electrochemotherapy (ECT) is a symptom control method for inoperable or exulcerating cutaneous metastases or skin cancer. With the help of electroporation, an enhancement of the efficacy of the administered chemotherapeutic agent, bleomycin or cisplatin, is achieved, which leads to a local reduction of the metastases and thereby has a low impact on the
Christian, Volberg, Martin, Gschnell
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Electrochemotherapy is a veterinary treatment used in horses to manage certain skin tumors, including sarcoids, mast cell tumors, and carcinomas. The therapy combines a chemotherapeutic drug, such as cisplatin or bleomycin, with brief electrical pulses applied directly to the tumor.
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[Progress in electrochemotherapy].
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2005Electrochemotherapy (ECT) is a novel cancer treatment in which electric pulses (EPs) inducing cell membrane pored (electroporation) are used as a means of delivering antitumor drugs to the cytoplasm of cancer cells. The minimal thresholds of electric field strength of in vitro tumor cell line and tumor tissue are 450-650 V/cm and 400-600 V/cm ...
Kong, Yang, Bisong, Yue, Zishu, Wang
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Electrochemotherapy in veterinary medicine
2007Electrochemotherapy is a treatment that combines electroporation, i.e. application of electric pulses to the tumors, that induces under suitable conditions reversible permeabilization of cell membrane and administration of nonpermeant or poorly permeant chemotherapeutic drugs with intracellular targets, whose entry into the cells is facilitated by ...
Nataša Tozon, Maja Cemazar
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Electrochemotherapy in dogs and cats–A review
Veterinary and Comparative OncologyAbstractElectrochemotherapy (ECT) is a treatment modality that combines the electroporation of cell membranes with chemotherapy to facilitate the transport of non‐permeant molecules into cells. Several canine and feline studies have shown promising results, suggesting that ECT can be a valid adjuvant or alternative treatment option for some tumours ...
Sofia Chichorro Ramos +4 more
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Electrochemotherapy for metastatic cutaneous melanoma
Acta Oncologica, 2022Bastrup, Freya A. +2 more
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Electrochemotherapy in Gorlin-Goltz syndrome
Italian Journal of Dermatology and Venereology, 2022Emanuele, Miraglia +5 more
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