Results 161 to 170 of about 4,009 (203)
Electrochemotherapy for Breast Cancer
Skin metastases occur more commonly in breast cancer (BC) than in any other malignancy in women, exceeding 20 % of all cutaneous metastases. They most commonly present on the chest wall (CW), but the abdomen, back, scalp, and upper extremities also are sites of occurrence. Presentation may be ambiguous; nevertheless, their local progression may lead to
CAMPANA, LUCA GIOVANNI +3 more
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Electrochemotherapy of melanoma cutaneous metastases
Az elektrokemoterápia daganatok bőráttéteinek palliatív kezelésére alkalmas eljárás, amelynek során nagy energiájú elektromos impulzusok hatására a sejtek membránja áteresztővé válik olyan anyagok, így kemoterapeutikumok számára, amelyek egyébként nem vagy csak kismértékben kerülnének a sejt belsejébe, ezáltal megnövelve azok citotoxikus hatását ...
Erika, Kis +5 more
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In Vitro and In Vivo Experiments on Electrochemotherapy for Bladder Cancer
PURPOSE: Electrochemotherapy is widely performed to treat solid tumors but experience with bladder cancer is limited. We investigated mitomycin C and cisplatin administered with electrochemotherapy for bladder cancer in vitro and in vivo.MATERIALS AND ...
Julie Gehl
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A metastasis of hypernephroma was treated by electrochemotherapy with bleomycin. Electrochemotherapy consists of chemotherapy followed by local application of electric pulses to the tumor in order to increase drug delivery to the cells. In the course of
Maja Čemažar +2 more
exaly +2 more sources
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Mechanisms of electrochemotherapy
Advanced Drug Delivery Reviews, 1999Electrochemotherapy is a new therapeutic approach providing delivery into cell interiors of nonpermeant drugs with intracellular targets. It is based on the local application of short and intense electric pulses that transiently permeabilize cells in tissues. To date, its main application has been the treatment of tumor nodules when the electric pulses
, Mir, , Orlowski
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The Basis of Electrochemotherapy
2003Antitumor electrochemotherapy is a treatment of solid tumors which combines a cytotoxic nonpermeant drug, like bleomycin, with locally delivered permeabilizing electric pulses (1-3). More generally, a new form of vectorization is achieved by the combination of nonpermeant molecules with intracellular targets and of a physical perturbation that locally ...
L M, Mir, S, Orlowski
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Electrochemotherapy for digital chondrosarcoma
Journal of Orthopaedic Science, 2003Electrochemotherapy (ECT) delivers nonpermeable anticancer drugs to cell interiors by temporally increasing the permeability of the cytoplasmic membrane under locally applied pulsating electrical stimuli. This treatment results in consistent and enhanced pharmacological effects of drugs on the targeted tissue.
Tominaga Shimizu +8 more
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Clinical applications of electrochemotherapy
Advanced Drug Delivery Reviews, 1999Electrochemotherapy is a novel treatment which consists of a combination of a chemotherapeutic agent and pulsed electric fields. This relatively new treatment modality relies on the physical effects of locally applied electric fields to temporarily destabilize cell membranes in the presence of a drug to allow increased uptake of the agent into the ...
, Heller, , Gilbert, , Jaroszeski
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Electrochemotherapy pre‐treatment in primary squamous vulvar cancer. Our preliminary experience
BACKGROUND AND OBJECTIVES: Previous studies showed a local tumor control of 80% in patients with relapsed squamous cell vulvar cancer (V-SCC) treated with electrochemotherapy. These results encouraged electrochemotherapy use as neo-adjuvant treatment in
Barbara Corti +2 more
exaly +2 more sources
Utility of electrochemotherapy in melanoma treatment
Current Opinion in Oncology, 2012In the present study, the role of electrochemotherapy (ECT) in the advanced melanoma setting, either as alternative treatment modality to conventional therapies or as palliative care, is reviewed and the perspective to combine ECT with biological response modifiers and immunotherapeutic compounds is discussed.ECT refers to the combination of ...
Alessandro Testori +2 more
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