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Treatment of metastatic melanoma with electrochemotherapy
Journal of Surgical Oncology, 2013Superficially metastatic melanoma still represents a challenging situation for oncologists and a distressing condition for patients. In this circumstance, local treatment by electrochemotherapy, that is, the combination of brief permeabilizing electric pulses with a low‐toxicity anticancer drug, can be a valuable treatment option in selected patients ...
Luca G, Campana +3 more
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Electrochemotherapy in veterinary medicine
2007Electrochemotherapy is a treatment that combines electroporation, i.e. application of electric pulses to the tumors, that induces under suitable conditions reversible permeabilization of cell membrane and administration of nonpermeant or poorly permeant chemotherapeutic drugs with intracellular targets, whose entry into the cells is facilitated by ...
Nataša Tozon, Maja Cemazar
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Electrochemotherapy: Animal Model Work Review
2003The major disadvantage of clinically established chemotherapeutic agents is their lack of selectivity for tumor cells. Therefore, for a pronounced antitumor effect, high doses of the chemotherapeutic drugs are needed, which often cause systemic toxicity and severe side effects.
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Treatment of Rat Glioma With Electrochemotherapy
2003The first attempt to apply electrochemotherapy (ECT) to the brain was reported in 1993 by Salford et al. 1993 (1). They managed to significantly prolong the survival of RG2 glioma bearing Fischer-344 rats by 200% by iv administration of bleomycin followed by intracranial electrochemotherapy with exponential decaying pulses.
L G, Salford, P, Engström, B R, Persson
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Electrochemotherapy of Breast Cancer
2017Electrochemotherapy is an emerging, minimally invasive treatment modality for unresectable skin tumors and cutaneous metastases. It combines the administration of a cytotoxic agent, bleomycin, or cisplatin, with the local application of brief electric pulses, in order to permeabilize tumor cell membrane and achieve effective drug delivery.
Luca G. Campana +3 more
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Electrochemotherapy for metastatic cutaneous melanoma
Acta Oncologica, 2022Bastrup, Freya A. +2 more
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CLINICAL APPLICATIONS OF ELECTROCHEMOTHERAPY
HEART AND …, 2019Electroporation has several biomedical and industrial applications. The biomedical applications are in the field of drug or gene delivery. Electrochemotherapy utilizes electroporation for the increased delivery of cytotoxic drugs like bleomycin or cisplatin into tumors.
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Electrochemotherapy for Breast Cancer
2016Skin metastases occur more commonly in breast cancer (BC) than in any other malignancy in women, exceeding 20 % of all cutaneous metastases. They most commonly present on the chest wall (CW), but the abdomen, back, scalp, and upper extremities also are sites of occurrence. Presentation may be ambiguous; nevertheless, their local progression may lead to
CAMPANA, LUCA GIOVANNI +3 more
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Electrochemotherapy in Gorlin-Goltz syndrome
Italian Journal of Dermatology and Venereology, 2022Emanuele, Miraglia +5 more
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