Results 71 to 80 of about 8,251,356 (397)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Development of a practical multicomponent density functional for electron-proton correlation to produce accurate proton densities. [PDF]
Multicomponent density functional theory (DFT) enables the consistent quantum mechanical treatment of both electrons and protons. A major challenge has been the design of electron-proton correlation (epc) functionals that produce even qualitatively ...
Yang Yang +4 more
semanticscholar +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Electron Densities, Momentum Densities, and Density Matrices
Abstract Relationships among electron coordinate-space and momentum densities and the one-electron charge density matrix or Wigner function are examined. A knowledge of either or both densities places constraints on possible density matrices.
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
The article presents the developed artificial neural network for F2 ionosphere layer traces scaling on ionograms obtained using the IPS-42 ionosonde installed at the Ukrainian Antarctic Akademik Vernadsky station.
O. Bogomaz +4 more
doaj +1 more source
Modeling of the cold electron plasma density for radiation belt physics
This review focusses strictly on existing plasma density models, including ionospheric source models, empirical density models, physics-based and machine-learning density models.
J.-F. Ripoll +12 more
doaj +1 more source
The Uppsala Electron-Density Server [PDF]
The Uppsala Electron Density Server (EDS; http://eds.bmc.uu.se/) is a web-based facility that provides access to electron-density maps and statistics concerning the fit of crystal structures and their maps. Maps are available for approximately 87% of the crystallographic Protein Data Bank (PDB) entries for which structure factors have been deposited ...
Gerard J, Kleywegt +5 more
openaire +2 more sources
Spatial structure of an incompressible Quantum Hall strip
The incompressible Quantum Hall strip is sensitive to charging of localized states in the cyclotron gap. We study the effect of localized states by a density functional approach and find electron density and the strip width as a function of the density ...
Chklovskii +9 more
core +2 more sources

