Results 71 to 80 of about 957,679 (377)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Sphingosine‐1‐phosphate receptor modulators (S1PRM) are used to treat relapsing multiple sclerosis (MS). Each drug has a different S1PR‐subtype selectivity. They target the G‐protein coupled S1P receptors and exert significant immunomodulatory effects, such as preventing the formation of new CNS lesions and the reactivation of pre ...
Faizan Shahzad +8 more
wiley +1 more source
Pioneers on the air: BBC radio broadcasts on computers and A.I., 1946-56 [PDF]
, 2002 Between 1946 and 1956, a number of BBC radio broadcasts were made by pioneers in the fields of computing, artificial intelligence and cybernetics. Although no sound recordings of the broadcasts survive, transcripts are held at the BBC's Written Archives ...
Jones, Allan
core
Quantum computing applied to calculations of molecular energies: CH2 benchmark
, 2010 Quantum computers are appealing for their ability to solve some tasks much faster than their classical counterparts. It was shown in [Aspuru-Guzik et al., Science 309, 1704 (2005)] that they, if available, would be able to perform the full configuration ...
Pittner, Jiří, Veis, Libor
core +1 more source
Simulating chemistry using quantum computers [PDF]
, 2010 The difficulty of simulating quantum systems, well-known to quantum chemists, prompted the idea of quantum computation. One can avoid the steep scaling associated with the exact simulation of increasingly large quantum systems on conventional computers ...
Alejandro Perdomo-Ortiz +14 more
core +2 more sources
ACTINIDE MOLECULAR SCIENCE: F-ELECTRONIC STRUCTURE IN SYNTHESIS, SPECTROSCOPY, AND COMPUTATION [PDF]
, 2000 This report focuses on the understanding of the relative roles of 5f/6d electronics on chemical bonding the relative roles of the iconic and covalent behaviors and polar and nonpolar solvents in controlling actinide chemical reactivity.
Berg, J., Burns, C., Al, Et
openaire +3 more sources
Understanding Mechanisms of Whole Brain and Regional Grey Matter Atrophy in Children With MOGAD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To investigate the mechanisms driving whole brain and regional grey matter (GM) volume changes along with their clinical correlates in paediatric myelin oligodendrocyte glycoprotein antibody (MOG‐Ab)–associated disease (MOGAD). Methods One‐hundred‐nine paediatric MOGAD patients from two UK centres underwent MRI at attack nadir and ...
Ermelinda De Meo +14 more
wiley +1 more source
Real‐World Comparison of High‐Efficacy Versus Non‐High‐Efficacy Therapies in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The choice of the first disease modifying treatment (DMT) in multiple sclerosis (MS) is a topic of great interest, and whether high‐efficacy DMTs should be the first choice remains debated. We compared treatment outcomes (no evidence of disease activity [NEDA] and its components) between treatment‐naïve relapsing–remitting MS (RRMS ...
Sarmad Al‐Araji +9 more
wiley +1 more source
Message and Medium: The Role of Social and Individual Factors in Using Computer Mediated Communications [PDF]
, 1998 The proliferation of computers and technology has resulted in increased use of computer mediated communications. However, the effective use of technology like bulletin boards and e-mail based communications can only be obtained if we understand how to ...
Ainspan , Nathan D. +1 more
core +1 more source
Usability dimensions in collaborative GIS [PDF]
, 2006 Collaborative GIS requires careful consideration of the Human-Computer Interaction (HCI) and Usability aspects, given the variety of users that are expected to use these systems, and the need to ensure that users will find the system effective, efficient,
Haklay, MM
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinal muscular atrophy (SMA) significantly impacts motor function. This study aimed to assess the persistent burden and unmet needs among currently treated patients with SMA and their caregivers. Methods Two complementary web‐based surveys were distributed in August 2024 among patients with SMA and their caregivers.
Julie A. Parsons +8 more
wiley +1 more source