Results 161 to 170 of about 210,230 (307)

Piezo1 Upregulation in Monocyte‐Derived Macrophages Impairs Post‐Myocardial Infarction Cardiac Repair via Defective Efferocytosis and Enhanced Ferroptosis

open access: yesAdvanced Science, EarlyView.
This study reports early Piezo1 activation in bone marrow monocyte‐derived macrophages (MoMs) during myocardial infarction (MI), which governs the fate and function of recruited macrophages. The recruited MoMs with increased Piezo1 expression exhibit increased ferroptosis and defective efferocytosis, delayed clearance of dead cells and resolution of ...
Lu Peng   +19 more
wiley   +1 more source

Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium Homeostasis

open access: yesAdvanced Science, EarlyView.
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu   +15 more
wiley   +1 more source

A Novel Feature Extraction Approach Using Window Function Capturing and QPSO-SVM for Enhancing Electronic Nose Performance [PDF]

open access: gold, 2015
Xiuzhen Guo   +7 more
openalex   +1 more source

Application of Machine Learning Algorithms to Classify Peruvian Pisco Varieties Using an Electronic Nose [PDF]

open access: gold, 2023
Celso De La Cruz   +7 more
openalex   +1 more source

Smoking‐Induced STC2+ Tumor Cells Drive Tumor‐Vascular Crosstalk in Laryngeal Squamous Cell Carcinoma via Spatial and Single‐Cell Transcriptomics

open access: yesAdvanced Science, EarlyView.
This study identifies a smoking‐induced mechanism in LSCC whereby nicotine activates the CHRNA5–JAK2/STAT3 axis to drive STC2 transcription. STC2 upregulates TGFBI, which interacts with endothelial ITGA5 to regulate vascular permeability and promote metastasis.
Yujie Shen   +5 more
wiley   +1 more source

Microglial Feimin Alleviates Cognitive Impairment in High‐Fat Diet‐Fed Mice

open access: yesAdvanced Science, EarlyView.
Microglial feimin deletion exacerbates lipotoxicity‐induced neuroinflammation and cognitive decline. In both in vitro and in vivo models, loss of feimin aggravated lipid droplet accumulation, IL‐1β/IL‐6 release, and neuronal injury through the PI3K–AKT–mTOR pathway, ultimately leading to severe neuronal apoptosis and cognitive impairment under high‐fat
Ran Gao   +12 more
wiley   +1 more source

Nature‐Inspired Innovation in Electrical Engineering Technologies and Applications

open access: yesAdvanced Science, EarlyView.
This review investigates how nature‐inspired design principles revolutionize electrical engineering by translating biological mechanisms, such as sensing, actuation, energy conversion, and neural processing, into advanced intelligent technologies. Through interdisciplinary integration, biomimetic strategies enable efficient, adaptive, and sustainable ...
Ming Li   +6 more
wiley   +1 more source

Electronic nose for detecting abnormal glucose metabolism in heart transplant recipients. [PDF]

open access: yesCardiovasc Diabetol
Wijbenga N   +11 more
europepmc   +1 more source

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