Results 51 to 60 of about 3,712,100 (312)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Factors Influencing the Biological Effects of FLASH Irradiation
AntioxidantsAmong the methods for increasing the specificity of tumor radiotherapy, FLASH radiotherapy (FLASH-RT) stands out, having recently entered clinical trials.
Sergey Igorevich Glukhov +2 more
doaj +1 more source
Implications of Kappa Suprathermal Halo of the Solar Wind Electrons
Frontiers in Astronomy and Space Sciences, 2022 The electron velocity distributions measured in-situ in space plasmas reveal two central populations, a low-energy and highly dense (quasi-)thermal core, and a more diffuse but hotter suprathermal halo. Even if the core contributes much more to the total
Viviane Pierrard +5 more
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
High Energy Electron-Electron Scattering [PDF]
Physical Review, 1952 Eradicated electron sensitive nuclear emulsions were exposed to 200-Mev electrons at the Berkeley synchrotron. In scanning the electron tracks 427 events were observed in which the scattered electron of lower energy, or knock-on electron, had an energy greater than 30 kev.
Barkas, Walter H. +3 more
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
East European Journal of PhysicsThis study investigates the kinetic properties of both symmetrical and asymmetrical multilayer and nano-sized semiconductor structures. We develop a theoretical framework using various models and mathematical methods to solve the Schrödinger matrix ...
Rustam Y. Rasulov +4 more
doaj +1 more source
New methodological approaches to the simultaneous measurement of the 90Sr and 137Cs activity in environmental samples [PDF]
Ядерна фізика та енергетика, 2012 Nonradiochemical method of measurement of 90Sr and137Cs activity in environmental samples is proposed. This method is based on spectrometrical investigation of electrons accompanied the decay of the 90Sr and137Cs.
M. V. Zheltonozhska +4 more
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