Results 71 to 80 of about 515,492 (292)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Assessing electron heat flux dropouts as signatures of magnetic field line disconnection from the Sun [PDF]

, 2005
Suprathermal electrons focused along magnetic field lines, called the strahl, carry heat flux away from the Sun. Various factors can cause heat flux dropouts (HFDs), including times when the strahl almost vanishes.
Larson, DE, D. E. Larson, C. Pagel, Crooker, NU, Pagel, C, N. U. Crooker   +5 more
core   +1 more source

Analysis of Kinetic Properties and Tunnel-Coupled States in Asymmetrical Multilayer Semiconductor Structures

East European Journal of Physics
This study investigates the kinetic properties of both symmetrical and asymmetrical multilayer and nano-sized semiconductor structures. We develop a theoretical framework using various models and mathematical methods to solve the Schrödinger matrix ...
Rustam Y. Rasulov, Vokhob R. Rasulov, Kamolakhon K. Urinova, Islombek A. Muminov, Bakhodir B. Akhmedov   +4 more
doaj   +1 more source

New methodological approaches to the simultaneous measurement of the 90Sr and 137Cs activity in environmental samples [PDF]

Ядерна фізика та енергетика, 2012
Nonradiochemical method of measurement of 90Sr and137Cs activity in environmental samples is proposed. This method is based on spectrometrical investigation of electrons accompanied the decay of the 90Sr and137Cs.
M. V. Zheltonozhska, N. V. Kulich, A. I. Lypska, V. I. Nikolaev, M. V. Strilchuk   +4 more
doaj  

‘Twisted’ electrons

Contemporary Physics, 2018
Electrons have played a significant role in the development of many fields of physics during the last century. The interest surrounding them mostly involved their wave-like features prescribed by the quantum theory. In particular, these features correctly predict the behaviour of electrons in various physical systems including atoms, molecules, solid ...
Hugo Larocque, Ido Kaminer, Vincenzo Grillo, Gerd Leuchs, Miles J Padgett, Robert W Boyd, Mordechai Segev, Ebrahim Karimi   +7 more
openaire   +3 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Influence of 2 MeV electrons irradiation on gallium phosphide light-emitting diodes reverse currents

Ядерна фізика та енергетика, 2015
Results of reverse electrophysical characteristics study of red and green LEDs, initial and irradiated with 2 MeV electrons were given. It was found that reverse current was predominantly caused by carriers tunneling at Urev ≤ 9 V, and by the avalanche ...
V. G. Vorobiov, O. V. Konoreva, Ye. V. Malyi, M. B. Pinkovska, V. P. Tartachnyk, V. V. Shlapatska   +5 more
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source