Results 81 to 90 of about 1,193,818 (298)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

One-dimensional semirelativity for electrons in carbon nanotubes

, 2005
It is shown that the band structure of single-wall semiconducting carbon nanotubes (CNT) is analogous to relativistic description of electrons in vacuum, with the maximum velocity $u$= $10^8$cm/s replacing the light velocity.
E. Schrödinger, J. A. Eisele, M. E. Rose, M. Katsnelson, R. Saito, W. Greiner, W. Zawadzki, Wlodek Zawadzki, Z. Ya. Kosakovskaya, Z. Ya. Kosakovskaya   +9 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Magnetospheric electrons [PDF]

Coupling of source, transport, and sink processes produces a fairly accurate model for the macroscopic structure and dynamics of magnetospheric electrons.
Coroniti, F. V., Thorne, R. M.
core   +1 more source

Nature of electron Zitterbewegung in crystalline solids

, 2009
We demonstrate both classically and quantum mechanically that the Zitterbewegung (ZB, the trembling motion) of electrons in crystalline solids is nothing else, but oscillations of velocity assuring the energy conservation when the electron moves in a ...
Barut, Bjorken, Cserti, Demikhovskii, Englman, Ferrari, Gerritsma, Huang, Jiang, Kane, Katsnelson, Krekora, Kronig, Lock, Luttinger, Lyssenko, Messiah, Romera, Rusin, Rusin, Rusin, Rusin, Schliemann, Schliemann, Schrödinger, Smith, Tomasz M. Rusin, Trauzettel, Vonsovsky, Winkler, Wlodek Zawadzki, Zawadzki, Zawadzki, Zawadzki, Zawadzki, Zhang, Zulicke   +36 more
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

On the spatially periodic ordering in the system of electrons above the surface of liquid helium in an external electric field

Condensed Matter Physics, 2018
A theory of equilibrium states of electrons above a liquid helium surface in the presence of an external clamping field is built based on the first principles of quantum statistics for the system of many identical Fermi-particles.
D.M. Lytvynenko, Yu.V. Slyusarenko, A.I. Kirdin   +2 more
doaj   +1 more source

Nonlinear Development of Streaming Instabilities In Strongly Magnetized Plasmas

, 2009
The nonlinear development of streaming instabilities in the current layers formed during magnetic reconnection with a guide field is explored. Theory and 3-D particle-in-cell simulations reveal two distinct phases. First, the parallel Buneman instability
A. A. Galeev, A. A. Galeev, H. Che, J. F. Drake, M. Swisdak, P. H. Yoon   +5 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source