Results 61 to 70 of about 515,492 (292)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Implications of Kappa Suprathermal Halo of the Solar Wind Electrons

Frontiers in Astronomy and Space Sciences, 2022
The electron velocity distributions measured in-situ in space plasmas reveal two central populations, a low-energy and highly dense (quasi-)thermal core, and a more diffuse but hotter suprathermal halo. Even if the core contributes much more to the total
Viviane Pierrard, Viviane Pierrard, Marian Lazar, Marian Lazar, Stepan Stverak, Stepan Stverak   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Statistics of counter-streaming solar wind suprathermal electrons at solar minimum : STEREO observations [PDF]

, 2010
Previous work has shown that solar wind suprathermal electrons can display a number of features in terms of their anisotropy. Of importance is the occurrence of counter-streaming electron patterns, i.e., with "beams" both parallel and anti-parallel to ...
Skoug, R. M., C. Mazelle, A. Opitz, Luhmann, J.G., E. Penou, Penou, E., C. Jacquey, Génot, Vincent, Larson, D. E., Jian, L., Sauvaud, J.-A., Fedorov, A., Jacquey, C.J., P. Schroeder, Gosling, J.T., Skoug, R.M., R. M. Skoug, Jacquey, C., K. D. Simunac, Meziane, K., Russell, C. T., Lavraud, B., C. Foullon, Foullon, C., J.-A. Sauvaud, Sauvaud, Jean-André, Rouillard, A.P., I. Dandouras, Rouillard, A. P., Génot, V., Luhmann, J. G., J. T. Gosling, C. T. Russell, J. T. Steinberg, Foullon, C. (Claire), A. B. Galvin, Opitz, A., Simunac, K. D., Larson, D.E., K. Meziane, Mazelle, C., Foullon, Claire, A. Fedorov, Galvin, A. B., J. G. Luhmann, Sauvaud, J.A., P. Louarn, Russell, C. T. (Christopher T.), Steinberg, John Tyree, D. E. Larson, Dandouras, I., Steinberg, J. T., Simunac, K.D.C., A. P. Rouillard, Schroeder, P., Russell, C.T., Galvin, A.B., Steinberg, J.T., Gosling, J. T., L. Jian, Louarn, P., V. Génot, B. Lavraud   +62 more
core   +2 more sources

Cyclotron acceleration of radiation belt electrons by whistlers

, 2003
The work considers the non linear scattering of energetic electrons in the earth's radiation belts due to cyclotron interaction with VLF whistlers.
Nunn, D, Rycroft, MJ, Demekhov, AG, Trakhtengerts, VY   +3 more
core   +1 more source

Electron-Electron Interactions in Artificial Graphene

Physical Review Letters, 2012
Recent advances in the creation and modulation of graphene-like systems are introducing a science of "designer Dirac materials". In its original definition, artificial graphene is a man-made nanostructure that consists of identical potential wells (quantum dots) arranged in a adjustable honeycomb lattice in the two-dimensional electron gas.
Rasanen E, Rozzi C A, Pittalis S, Vignale G   +3 more
openaire   +5 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Electrons in the cosmic radiation [PDF]

, 1990
The nature of cosmic ray electrons and their radiation in the Universe has been studied. A convection associated diffusion model is proposed to describe the main characteristics of the large-scale distribution of cosmic ray electrons in the Galaxy: (1) a
Chi, Xinyu, Chi, X
core  

Comparison of the characteristic energy of precipitating electrons derived from ground-based and DMSP satellite data [PDF]

, 2005
International audienceEnergy maps are important for ionosphere-magnetosphere coupling studies, because quantitative determination of field-aligned currents requires knowledge of the conductances and their spatial gradients.
M. Ashrafi, Ashrafi, M., Kosch, M. J., M. J. Kosch, F. Honary, Honary, F.   +5 more
core   +2 more sources

Factors Influencing the Biological Effects of FLASH Irradiation

Antioxidants
Among the methods for increasing the specificity of tumor radiotherapy, FLASH radiotherapy (FLASH-RT) stands out, having recently entered clinical trials.
Sergey Igorevich Glukhov, Elena Ananievna Kuznetsova, Sergey Vsevolodovich Akulinichev   +2 more
doaj   +1 more source