Results 201 to 210 of about 43,957 (340)
Quantitative Mapping of NHS Ester-Protein Reactivity Using Native Top-Down Mass Spectrometry. [PDF]
Bennett JL +4 more
europepmc +1 more source
Internal Ubiquitin Electrophiles for Covalent Trapping and Inhibition of Deubiquitinases [PDF]
Nipuni M. Pannala +7 more
openalex +1 more source
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos +4 more
wiley +1 more source
Enantio- and Site-Selective Synthesis of α-Substituted Hydrazines, Pyrazolidines, and Tertiary Alcohols by Copper-Catalyzed Allylic C-N and C-O Bond Formation. [PDF]
Johnson BE +3 more
europepmc +1 more source
Quasi T‐shaped three‐way benzo[b]thiophene scaffolds, containing iodine atom(s) at the 4‐ and/or 7‐position, were prepared by several methods such as silica gel‐assisted cyclization. The iodobenzo[b]thiophenes thus prepared were subjected to Sonogashira cross couplings to give various ethynylbenzo[b]thiophenes.
Kozo Toyota +9 more
wiley +1 more source
Mo-Catalyzed Asymmetric Allylic Alkylation Enabling the Construction of Highly Enantioenriched 1,4-Dicarbonyl Scaffolds. [PDF]
Cerione CS, Moghadam FA, Stoltz BM.
europepmc +1 more source
We investigate tip‐induced bond weakening of a single alkyne center immobilized and aligned upright on Au(111) using a rigid triphenylmethane‐based tripod. By varying the tip–molecule distance, we observe shifts in the ≡C–H and –C≡C– vibrational bands via ultrahigh vacuum low‐temperature tip‐enhanced Raman scattering (TERS).
Gang Li +12 more
wiley +1 more source
Discovery of RNA-Reactive Small Molecules Guides the Design of Electrophilic Modules for RNA-Specific Covalent Binders. [PDF]
Springer NA +4 more
europepmc +1 more source
Synthesis of C59(CHPh2)N from (C59N)2 and C59HN. The First Derivatization of C59N [PDF]
Bellavia-Lund, Cheryl, +5 more
core +3 more sources

