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Regulation of Nrf2—an update [PDF]
Free Radical Biology and Medicine, 2014 Nrf2:INrf2 (Keap1) are cellular sensors of oxidative and electrophilic stress. Nrf2 is a nuclear factor that controls the expression and coordinated induction of a battery of genes that encode detoxifying enzymes, drug transporters, antiapoptotic proteins, and proteasomes.
Suryakant K Niture +2 more
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Nrf2-Keap1 signaling in oxidative and reductive stress
Biochimica Et Biophysica Acta - Molecular Cell Research, 2018Ilaria Bellezza +2 more
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Modulating NRF2 in Disease: Timing Is Everything
Annual Review of Pharmacology and Toxicology, 2019Montserrat Rojo De La Vega +2 more
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The Keap1–Nrf2–ARE Pathway As a Potential Preventive and Therapeutic Target: An Update
Medicinal Research Reviews, 2016Meng-Chen Lu +2 more
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The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer
Redox Biology, 2013Emilia Kansanen +2 more
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Molecular basis of the Keap1–Nrf2 system
Free Radical Biology and Medicine, 2015Takafumi Suzuki, Masayuki Yamamoto
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Transcriptional Regulation by Nrf2
Antioxidants and Redox Signaling, 2018Claudia Tonelli +2 more
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Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas
Cancer Cell, 2017Jelena Todoric +2 more
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Molecular mechanisms of Nrf2‐mediated antioxidant response
Molecular Carcinogenesis, 2009Ah-Ng Kong
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A clinical-stage Nrf2 activator suppresses osteoclast differentiation via the iron-ornithine axis
Cell MetabolismYimin Dong, Renpeng Peng, Meipeng Zhu
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