Results 1 to 10 of about 1,619,517 (405)

Electrophoresis of positioned nucleosomes [PDF]

Biophysical Journal, 2007
We present in this paper an original approach to compute the electrophoretic mobility of rigid nucleo-protein complexes like nucleosomes. This model allows to address theoretically the influence of complex position along DNA, as well as wrapped length of DNA on the electrophoretic mobility of the complex. The predictions of the model are in qualitative
Allison, Allison, Allison, Allison, Allison, Allison, Angelov, Bao, Beard, Brinkman, Castelnovo, de la Torre, Dorfman, Drak, Flaus, Henikoff, Huckel, Koo, Kunze, Levene, Lodish, Long, Long, Luger, Martin Castelnovo, Meersseman, Pennings, Pennings, Popelka, Rotne, Russel, Schiessel, Stigter, Sébastian Grauwin, Viovy, Yamakawa   +35 more
arxiv   +12 more sources

The repton model of gel electrophoresis [PDF]

Physica A 244, 25 (1997), 1996
We discuss the repton model of agarose gel electrophoresis of DNA. We review previous results, both analytic and numerical, as well as presenting a new numerical algorithm for the efficient simulation of the model, and suggesting a new approach to the model's analytic solution.
Barkema, Barkema, de Gennes, Derrida, Duke, Duke, Duke, Duke, G.T. Barkema, Kooiman, Kooiman, M.E.J. Newman, Prähofer, Rubinstein, Schütz, van Leeuwen, Widom, Widom   +17 more
arxiv   +3 more sources

Membrane proteins and proteomics: Love is possible, but so difficult [PDF]

Electrophoresis 30, S1 (2009) S174-S180, 2009
Despite decades of extensive research, the large-scale analysis of membrane proteins remains a difficult task. This is due to the fact that membrane proteins require a carefully balanced hydrophilic and lipophilic environment, which optimum varies with different proteins, while most protein chemistry methods work mainly, if not only, in water-based ...
Adessi, Aebersold, Aivaliotis, Aivaliotis, Alla, Ames, Babu, Bagshaw, Bell, Berlanda-Scorza, Berven, Bierczynska-Krzysik, Bisle, Bjellqvist, Bunai, Bunai, Burré, Buxbaum, Casey, Chevallet, Chevallet, Connolly, Coughenour, Cutillas, Devreese, Eravci, Everberg, Felsted, Ferro, Gatlin, Ghosh, Gyenes, Görg, Hagan, Hahne, Hartinger, Helling, Henningsen, Henzel, Hisabori, Hjelmeland, Huang, Huang, James, Jun, Lasonder, Lescuyer, Liberatori, Lopez, Low, Luche, Lyubimova, Lüddens, MacFarlane, MacFarlane, Matsudaira, McDonough, Miguet, Moebius, Molloy, Molloy, Nandakumar, Natera, Navarre, Ong, Papasotiriou, Pappin, Patton, Pedersen, Peng, Perdew, Phadke, Rabilloud, Rabilloud, Rabilloud, Rabilloud, Rabilloud, Rais, Rubin, Santoni, Santoni, Schindler, Schirle, Schägger, Siroy, Speers, Sweetnam, Switzer, Tastet, Taylor, Towbin, Veith, Washburn, Werner, Wilkins, Williams, Williams, Williams, Wittig, Witzmann, Wu, Yates, Ying, Zahedi   +103 more
arxiv   +5 more sources

Magnetophoresis of Tagged Polymers [PDF]

, 1996
We present quantitative results for the drift velocity of a polymer in a gel if a force (e.g. through an electric or magnetic field) acts on a tag, attached to one of its ends. This is done by introducing a modification of the Rubinstein-Duke model for electrophoresis of DNA.
Barkema, G. T., Schütz, G. M.
arxiv   +4 more sources

Release of protein N-glycans by effectors of a Hofmann carboxamide rearrangement

Frontiers in Molecular Biosciences, 2022
Background: Chemical methods for glycan release have gained traction because of their cost efficiency, accelerated reaction time and ability to release glycans not amenable to enzymatic cleavage.
Mumtaz Kasim, Malissa Schulz, Anja Griebel, Akshay Malhotra, Barbara Müller, Hans Henning von Horsten   +5 more
doaj   +1 more source

Seamless Coupling of Chemical Glycan Release and Labeling for an Accelerated Protein N-Glycan Sample Preparation Workflow

Bioengineering, 2023
Analytical methods fr direct quantitative N-glycan analysis require a sequence of sample preparation and clean-up steps that result in reduced glycan recovery. Therefore, we aimed to combine glycan release and labeling steps. Based on the hypothesis that
Mumtaz Kasim, Anja Griebel, Grit Sandig, Robert Höltzel, Akshay Malhotra, Stephan Hinderlich, Volker Sandig, Barbara Müller, Hans Henning von Horsten   +8 more
doaj   +1 more source

Reporting two hemoglobin J Iran cases, molecular follow-up, or is it insignificant? [PDF]

Caspian Journal of Internal Medicine, 2023
Background: Hemoglobin J is one of the fast hemoglobin that has a more negative charge due to β77His→Asp substitution. Acquisition of this hemoglobin is not associated with any specific clinical sign, but the combination of this hemoglobinopathy with ...
Amin Solouki, Tahereh Manoochehrabadi, Farzaneh Korani, Mohammadreza Farshchi   +3 more
doaj  

The Evolution of the Sickle Cell Anaemia in the Region of Kinshasa: a Mathematic Modelling

Hipotenusa, 2022
We attempt to study the evolution of the sickle cell anaemia in the region of Kinshasa by proposing three models based on Markov processes.  The first two models namely, the idealistic and the quasi- idealistic models fail to completely describe the data
R.Gilles Bokolo, Cedric Musema Sinamuli, Dibere Kodondi, Bruce Shola Mafuta   +3 more
doaj   +1 more source

Electrokinetic characterization of synthetic protein nanoparticles

Beilstein Journal of Nanotechnology, 2020
The application of nanoparticle in medicine is promising for the treatment of a wide variety of diseases. However, the slow progress in the field has resulted in relatively few therapies being translated into the clinic.
Daniel F. Quevedo, Cody J. Lentz, Adriana Coll de Peña, Yazmin Hernandez, Nahal Habibi, Rikako Miki, Joerg Lahann, Blanca H. Lapizco-Encinas   +7 more
doaj   +1 more source

Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA

Applied and Environmental Microbiology, 1993
We describe a new molecular approach to analyzing the genetic diversity of complex microbial populations. This technique is based on the separation of polymerase chain reaction-amplified fragments of genes coding for 16S rRNA, all the same length, by ...
G. Muyzer, E. Waal, A. Uitterlinden
semanticscholar   +1 more source