Results 101 to 110 of about 820,083 (349)
A simulation methodology for predicting the time-course of enzymatic digestions is described. The model is based solely on the enzyme's subsite architecture and concomitant binding energies.
Allen+45 more
core +1 more source
In this study, a fiber‐embedded drug delivery channel for implantable microprobes, demonstrating the first functional drug delivery system using flexible LCP‐based probes, is developed. The design incorporates fibers for site‐selective drug delivery and electrical functions. The utilization of monolithic thermal bonding simplifies fabrication.
Jaehwan Byun+6 more
wiley +1 more source
Capillary Electrophoresis for Sampling Single Nerve Cells
Two micro-capillary electrophoresis techniques are underdevelopment to acquire and determine catecholamines in single nerve cells. The first method involves the analysis of neurotransmitters in a portion of cytoplasm withdrawn from a single cell,
Teresa M. Olefirowicz, Andrew G. Ewing
doaj +2 more sources
A miniaturized microfluidic device is 3D printed via two‐photon polymerization and used for the droplet‐based microfluidic synthesis of nanogels for controlled drug delivery purposes. Tuning the fluid flow parameters, the microfluidic system enables the modulation of nanogel size and properties, preserving an extremely low polydispersity, beyond the ...
Vladimir Matining+8 more
wiley +1 more source
Clinical capillary electrophoresis
Abstract Capillary electrophoresis is a relatively new analytical technique that has begun to have an impact in the clinical laboratory, both for routine analyses and for those that are more esoteric. Its potential for automated, rapid, high-efficiency separations makes it appealing as a replacement for some of the more labor-intensive ...
openaire +2 more sources
Millimeter‐scale macroscopic phase‐change balls with on‐demand drug release triggered by photothermal stimulation and magnetically controllable transport properties are demonstrated. The proposed system can be easily fabricated using omniphobic surfaces and offers several advantages, including high visibility, controllable transport, easy drug loading,
Hyunji Lee+5 more
wiley +1 more source
From Lab to Market: Paper‐Based CRISPR Diagnostics and Commercialization Pathways
Paper‐based CRISPR diagnostics represents one of the most widely commercialized CRISPR assay technologies, yet challenges remain for broader point‐of‐care use. Abstract The global health landscape is continually challenged by infectious diseases that can swiftly escalate into pandemics, underscoring the need for rapid, accurate, and cost‐effective ...
Selen Dalgan, Qingshan Wei
wiley +1 more source
Background Capillary electrophoresis of plasma proteins has shown great potential as a complementary diagnostic tool for avian species. However, reference intervals for plasma proteins are sparse or lacking for several free-living avian species.
Jørgen Flo+4 more
doaj +1 more source
Optical sensing in microchip capillary electrophoresis by femtosecond laser written waveguides [PDF]
Capillary electrophoresis separation in an on-chip integrated microfluidic channel is typically monitored with bulky, bench-top optical excitation/detection instrumentation.
Cerullo, G.+9 more
core +1 more source
NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi+16 more
wiley +1 more source