Results 101 to 110 of about 820,083 (349)

On the simulation of enzymatic digest patterns: the fragmentation of oligomeric and polymeric galacturonides by endo-polygalacturonase II

open access: yes, 2006
A simulation methodology for predicting the time-course of enzymatic digestions is described. The model is based solely on the enzyme's subsite architecture and concomitant binding energies.
Allen   +45 more
core   +1 more source

Targeted Local Delivery via Fiber‐Embedded Flexible Microchannels Integrated with Film‐Based Implantable Probes

open access: yesAdvanced Materials Technologies, EarlyView.
In this study, a fiber‐embedded drug delivery channel for implantable microprobes, demonstrating the first functional drug delivery system using flexible LCP‐based probes, is developed. The design incorporates fibers for site‐selective drug delivery and electrical functions. The utilization of monolithic thermal bonding simplifies fabrication.
Jaehwan Byun   +6 more
wiley   +1 more source

Capillary Electrophoresis for Sampling Single Nerve Cells

open access: yesCHIMIA, 1991
Two micro-capillary electrophoresis techniques are underdevelopment to acquire and determine catecholamines in single nerve cells. The first method involves the analysis of neurotransmitters in a portion of cytoplasm withdrawn from a single cell,
Teresa M. Olefirowicz, Andrew G. Ewing
doaj   +2 more sources

Droplet‐Based Synthesis of Nanogels for Controlled Drug Delivery via Two Photon Polymerization‐3D Printed Microfluidic Device

open access: yesAdvanced Materials Technologies, EarlyView.
A miniaturized microfluidic device is 3D printed via two‐photon polymerization and used for the droplet‐based microfluidic synthesis of nanogels for controlled drug delivery purposes. Tuning the fluid flow parameters, the microfluidic system enables the modulation of nanogel size and properties, preserving an extremely low polydispersity, beyond the ...
Vladimir Matining   +8 more
wiley   +1 more source

Clinical capillary electrophoresis

open access: yesClinical Chemistry, 1995
Abstract Capillary electrophoresis is a relatively new analytical technique that has begun to have an impact in the clinical laboratory, both for routine analyses and for those that are more esoteric. Its potential for automated, rapid, high-efficiency separations makes it appealing as a replacement for some of the more labor-intensive ...
openaire   +2 more sources

Macroscopic Phase‐Change Drug Carrier Ball with Photothermally Controlled Release and Magnetically Controlled Transport Properties

open access: yesAdvanced Materials Technologies, EarlyView.
Millimeter‐scale macroscopic phase‐change balls with on‐demand drug release triggered by photothermal stimulation and magnetically controllable transport properties are demonstrated. The proposed system can be easily fabricated using omniphobic surfaces and offers several advantages, including high visibility, controllable transport, easy drug loading,
Hyunji Lee   +5 more
wiley   +1 more source

From Lab to Market: Paper‐Based CRISPR Diagnostics and Commercialization Pathways

open access: yesAdvanced Sensor Research, EarlyView.
Paper‐based CRISPR diagnostics represents one of the most widely commercialized CRISPR assay technologies, yet challenges remain for broader point‐of‐care use. Abstract The global health landscape is continually challenged by infectious diseases that can swiftly escalate into pandemics, underscoring the need for rapid, accurate, and cost‐effective ...
Selen Dalgan, Qingshan Wei
wiley   +1 more source

Plasma protein fractions in free-living white-tailed eagle (Haliaeetus albicilla) nestlings from Norway

open access: yesBMC Veterinary Research, 2019
Background Capillary electrophoresis of plasma proteins has shown great potential as a complementary diagnostic tool for avian species. However, reference intervals for plasma proteins are sparse or lacking for several free-living avian species.
Jørgen Flo   +4 more
doaj   +1 more source

Optical sensing in microchip capillary electrophoresis by femtosecond laser written waveguides [PDF]

open access: yes, 2009
Capillary electrophoresis separation in an on-chip integrated microfluidic channel is typically monitored with bulky, bench-top optical excitation/detection instrumentation.
Cerullo, G.   +9 more
core   +1 more source

NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea

open access: yesAdvanced Science, EarlyView.
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi   +16 more
wiley   +1 more source

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