Results 151 to 160 of about 205,159 (276)

Spider Eye Development Editing and Silk Fiber Engineering Using CRISPR‐Cas

open access: yesAngewandte Chemie International Edition, Accepted Article.
CRISPR‐Cas9 gene editing represents an effective and precise technology to induce mutations in the genome, and it has been applied to a wide range of organisms for diverse purposes. However, CRISPR‐based gene editing in spiders has not been reported to date.
Edgardo Santiago Rivera, Thomas Scheibel
wiley   +1 more source

Complex formation and enantioselectivity studies of triazole fungicide and organophosphorus pesticide enantiomers using capillary electrophoresis [PDF]

open access: yes, 2008
Several cyclodextrin modified-micellar electrokinetic chromatography (CDMEKC) methods were developed for the successful triazole fungicides separation.
Hermawan, Dadan   +2 more
core  

Optogenetic control of transgene expression in Marchantia polymorpha

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise The model liverwort Marchantia polymorpha is an emerging testbed species for plant metabolic engineering but lacks well‐characterized inducible promoters, which are necessary to minimize biochemical and physiological disruption when over‐accumulating target products.
Anya Lillemor Lindström Battle   +1 more
wiley   +1 more source

Senkyunolide I Improves Septicemia‐Induced Brain Dysfunction via Regulating Nrf2 and Astrocyte Activity.

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Senkyunolide I (Sen I) has a protective effect on the blood–brain barrier (BBB) in rats with sepsis‐associated encephalopathy (SAE). This study investigated whether Sen I regulates Nrf2 to ameliorate sepsis‐induced brain dysfunction (SIBD). Sixty rats were randomly assigned into Sham group, SAE group (Model group), SAE + Sen I group (72 mg/kg,
Haohao Cao, Tao Liu, Meixia Xu
wiley   +1 more source

Mono-\u3cem\u3eN\u3c/em\u3e-acyl-2,6-diaminopimelic Acid Derivatives: Analysis by Electromigration and Spectroscopic Methods and Examination of Enzyme Inhibitory Activity [PDF]

open access: yes, 2014
Thirteen mono-N-acyl derivatives of 2,6-diaminopimelic acid (DAP)—new potential inhibitors of the dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase (DapE; EC 3.5.1.18)—were analyzed and characterized by infrared (IR) and nuclear magnetic ...
Buděšínský, Miloš   +10 more
core   +1 more source

Combining face‐to‐face laboratory sessions and a computer simulation effectively teaches gene editing and DNA sequencing to undergraduate genetics students

open access: yesBiochemistry and Molecular Biology Education, EarlyView.
Abstract Innovative approaches to teaching genetics are essential for improving student engagement and comprehension in this challenging field. Laboratory‐based instruction enhances engagement with the subject while fostering the development of practical competencies and deepening comprehension of theoretical concepts.
Chris Della Vedova   +2 more
wiley   +1 more source

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

open access: yesBMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah   +9 more
wiley   +1 more source

Diagnostic value of capillary electrophoresis of blood serum proteins and urine in patients with multiple myeloma

open access: yesActa Biomedica Scientifica, 2013
The authors state that capillary electrophoresis of blood and urine proteins is one of the defining method in revealing and confirmation of the presence of paraprotein at multiple myeloma.
T. I. Trubnikova   +3 more
doaj  

Phytochemistry, Antibacterial and Antioxidant Activities of Grewia lasiocarpa E. Mey. Ex Harv. Fungal Endophytes: A Computational and Experimental Validation Study

open access: yesChemistry &Biodiversity, EarlyView.
Schematics workflow for the isolation and characterisation of endophytic fungi from grewia lasiocarpa and their biological activity. Abstract The genus Grewia are well‐known for their medicinal properties and are widely used in traditional remedies due to their rich phytochemical composition and potential health benefits.
Nneka Augustina Akwu   +7 more
wiley   +1 more source

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