Results 31 to 40 of about 43,524 (303)

Molecular Investigation of Tularemia Outbreaks, Spain, 1997–2008

Emerging Infectious Diseases, 2014
Tularemia outbreaks occurred in northwestern Spain in 1997–1998 and 2007–2008 and affected >1,000 persons. We assessed isolates involved in these outbreaks by using pulsed-field gel electrophoresis with 2 restriction enzymes and multilocus variable ...
Jaime Ariza-Miguel, Anders Johansson, María Isabel Fernández-Natal, Carmen Martínez-Nistal, Antonio Orduña, Elías F. Rodríguez-Ferri, Marta Hernández, David Rodríguez-Lázaro   +7 more
doaj   +1 more source

Genomic relatedness within five common Finnish Campylobacter jejuni pulsed-field gel electrophoresis genotypes studied by amplified fragment length polymorphism analysis, ribotyping and serotyping

, 2001
Thirty-five Finnish Campylobacter jejuni strains with five SmaI/SacII pulsed-field gel electrophoresis (PFGE) genotypes selected among human and chicken isolates from 1997 and 1998 were used for comparison of their PFGE patterns, amplified fragment ...
Hanninen, M.L., Wagenaar, J.A., Rautelin, H., Perko Makela, P., Duim, B.   +4 more
core   +1 more source

Salmonella enterica Pulsed-Field Gel Electrophoresis Clusters, Minnesota, USA, 2001–2007

Emerging Infectious Diseases, 2010
We determined characteristics of Salmonella enterica pulsed-field gel electrophoresis clusters that predict their being solved (i.e., that result in identification of a confirmed outbreak). Clusters were investigated by the Minnesota Department of Health
Joshua M. Rounds, Craig W. Hedberg, Stephanie Meyer, David J. Boxrud, Kirk E. Smith   +4 more
doaj   +1 more source

Pulsed-field Gel Electrophoresis for Salmonella Infection Surveillance, Texas, USA, 2007

Emerging Infectious Diseases, 2010
To identify sources of transmission for area clusters, in 2007 the Houston Department of Health and Human Services conducted an 8-month study of enhanced surveillance of Salmonella infection.
Stephen G. Long, Herbert L. DuPont, Linda Gaul, Raouf R. Arafat, Beatrice J. Selwyn, Joan Rogers, Eric Casey   +6 more
doaj   +1 more source

Understanding the molecular epidemiology of the footrot pathogen Dichelobacter nodosus to support control and eradication programs

, 2010
The Gram-negative anaerobe Dichelobacter nodosus is the primary etiologic agent of ovine footrot. Few studies of the genetic diversity and epidemiology of D. nodosus have been done, despite the economic cost and welfare implications of the disease.
Pitman, D., D. J. Hampson, Palmer, M., Hampson, D.J., N. B. Buller, Ashley, P., D. Pitman, R. B. Richards, Buller, N. B., Richards, R. B., P. Ashley, M. Palmer   +11 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Outbreak of Extended-Spectrum β-Lactamase–producing Klebsiella oxytoca Infections Associated with Contaminated Handwashing Sinks

Emerging Infectious Diseases, 2012
Klebsiella oxytoca is primarily a health care–associated pathogen acquired from environmental sources. During October 2006–March 2011, a total of 66 patients in a hospital in Toronto, Ontario, Canada, acquired class A extended-spectrum β-lactamase ...
Christopher Lowe, Barbara Willey, Anna O’Shaughnessy, Wayne Lee, Ming Lum, Karen Pike, Cindy Larocque, Helen Dedier, Lorraine Dales, Christine Moore, Allison McGeer   +10 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Serotype Panama: An exceptionally virulent cause of illness in children?

SAGE Open Medical Case Reports, 2019
Salmonella enterica serotype Panama accounts for
Stephanie M Parry, Aileen M Aldrich, Anna V Carlson, Sarah A Trotter, Peter C Iwen, Theodore J Cieslak   +5 more
doaj   +1 more source

Investigating Potential Chromosomal Rearrangements during Laboratory Culture of Neisseria gonorrhoeae

Microorganisms, 2018
Comparisons of genome sequence data between different strains and isolates of Neisseria spp., such as Neisseria gonorrhoeae, reveal that over the evolutionary history of these organisms, large scale chromosomal rearrangements have occurred.
Russell Spencer-Smith, Simon W. Gould, Madhuri Pulijala, Lori A. S. Snyder   +3 more
doaj   +1 more source