Results 111 to 120 of about 663,442 (290)

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

open access: yesAdvanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham   +9 more
wiley   +1 more source

KAPSEL: Kyoto Advanced Particle Simulator for ELectrohydrodynamics

open access: yesKONA Powder and Particle Journal, 2014
We have released a colloid simulator named KAPSEL implemented the “Smoothed Profile (SP) method” which has been developed by ourselves for direct numerical simulations of particulate flow providing a way
Ryoichi Yamamoto   +2 more
doaj   +1 more source

Methods for improved resolution of flow electrophoresis cells [PDF]

open access: yes, 1974
First method involves remote adjusting of zeta potential. Second approach sandwiches two conducting metal plates between opposite cell walls and thin insulating layer.
Fogal, G. L., Mccreight, L. R.
core   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

open access: yesAdvanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh   +3 more
wiley   +1 more source

The evaluation of effectiveness of nanoimpregnation in treatment of dental hyperesthesia in the settings of experimental study

open access: yesЭндодонтия Today, 2020
Nanoimpregnation with particles of copper hydroxide-calcium in treatment of dental hyperesthesia (experimental study). Based on the Branstrem's theory of development of dental hyperesthesia, reliable and deeper obturation of dentinal tubules with ...

doaj  

Fast Separation and Determination of Flavonoids in Honey Samples by Capillary Zone Electrophoresis [PDF]

open access: diamond, 2017
Jianqiu Tu   +5 more
openalex   +1 more source

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

open access: yesAdvanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila   +7 more
wiley   +1 more source

THE USE OF ENDONASAL ELECTROPHORESIS WITH MEXIDOL IN COMBINATION WITH ACUPUNCTURE IN THE TREATMENT OF PATIENTS WITH POST-COVID ANOSMIA

open access: diamond, 2022
Mustafa Al-Zamil   +9 more
openalex   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

open access: yesAdvanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu   +5 more
wiley   +1 more source

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