Results 71 to 80 of about 1,000,843 (316)

Multimer Analysis of Von Willebrand Factor in Von Willebrand Disease with a Hydrasys Semi-Automatic Analyzer—Single-Center Experience

Diagnostics, 2021
von Willebrand disease (VWD) is reportedly the most common inherited bleeding disorder. This disorder develops as a result of defects and/or deficiency of the plasma protein von Willebrand factor (VWF).
Ingrid Skornova, Tomas Simurda, Jan Stasko, Jana Zolkova, Juraj Sokol, Pavol Holly, Miroslava Dobrotova, Ivana Plamenova, Jan Hudecek, Monika Brunclikova, Alena Stryckova, Peter Kubisz   +11 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Application of capillary nongel sieving electrophoresis for gene analysis [PDF]

, 1999
Capillary electrophoresis (CE) has proved to be a strong tool for DNA analysis and has found abundant applications in the fields of restriction fragment sizing, mutation screening, polymerase chain reaction (PCR) product characterizing and forensic ...
Zhu, N, Song, F, Shen, Y, Ding, K, Xu, Q, Han, FT, Fan, Y, Wu, GY, Lin, BC   +8 more
core  

Gel Electrophoresis

Clinical Chemistry, 1962
Abstract Gel electrophoresis is discussed and it is shown that this medium is still in the developmental stage for the resolution of serum proteins. It is the procedure of choice for the analysis of hemoglobins.
S, RAYMOND, M, NAKAMICHI
openaire   +2 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Analysis of biopharma raw materials by electrophoresis microchips with contactless conductivity detection [PDF]

, 2009
Detailed information concerning the composition of the raw materials employed in the production of biologics is important for the efficient control and optimization of bioprocesses.
Benito-Lopez, Fernando, Ricco, Antonio J., Vázquez, Mercedes, Diamond, Dermot, Garcia-Cordero, Jose L.   +4 more
core  

Proteomic methods for separation and identification of milk proteins

Пищевые системы
The review presents the most common proteomics methods based on separation and identification of proteins, with examples of their use for studying the protein system of milk and dairy products.
O. V. Lepilkina, A. I. Grigorieva
doaj   +1 more source

Evaluation of the effects of tropical tanniferous plants on rumen microbiota using qRT PCR and DGGE analysis

Czech Journal of Animal Science, 2013
Tanniferous forages may have bacteriostatic and/or bactericidal effect on different rumen microbial populations. We investigated the influence of the tropical tanniferous plants Styzolobium aterrimum (STA), Styzolobium deeringianum (STD), Leucaena ...
C. Longo, A.L. Abdalla, J. Liebich, I. Janzik, J. Hummel, P.S. Correa, K.-H. Südekum, P. Burauel   +7 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Localized Amyloidosis of the Oral Cavity: A Rare Clinical Entity

Clinical Case Reports
Amyloidosis is a complex disease which rarely affects the oral cavity. While localized and systemic variants have a similar clinical presentation, these entities differ vastly in their natural history and prognosis.
Brian Maloney, Veronica Fisher, Claire M. Healy   +2 more
doaj   +1 more source