Results 231 to 240 of about 192,083 (323)

Imaging activity in astrocytes and neurons with genetically encoded calcium indicators following in utero electroporation [PDF]

, 2015
James M Gee, Meredith B. Gibbons, Marsa Taheri, Sierra Palumbos, S. Craig Morris, Roy M. Smeal, Katherine F. Flynn, Michael N. Economo, Christian G. Cizek, Mario R. Capecchi, Petr Tvrdík, Karen S. Wilcox, John A. White   +12 more
openalex   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

A step-by-step approach to establishing an efficient genetic transformation protocol for Chlorella vulgaris using electroporation. [PDF]

Mol Biol Rep
Robben DM, Amin Z, Budiman C, Kumar VS.
europepmc   +1 more source

Electroporation by using bipolar oscillating electric field: an improved method for DNA transfection of NIH 3T3 cells.

, 1991
Ephrem Tekle, R. Dean Astumian, P Boon Chock   +2 more
openalex   +2 more sources

Asymptotic Analysis of the Static Bidomain Model for Pulsed Field Cardiac Ablation

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT Cardiac arrhythmias are caused by faulty electrical signals in the heart, which lead to chaotic wave propagation and impaired cardiac function. This work focuses on a non‐thermal ablation technique based on electroporation (EP), a promising method for treating arrhythmias, called pulsed field ablation (PFA).
Annabelle Collin, Simone Nati Poltri, Clair Poignard   +2 more
wiley   +1 more source

MicroRNA-138 regulation promotes the efficacy of oncolytic herpes virus G47Δ for malignant brain tumor therapy. [PDF]

Mol Ther Oncol
Kanayama S, Haraguchi T, Iba H, Tanaka M, Todo T.   +4 more
europepmc   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

ChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel, Mohammed Al‐zharani, Lina M. Alneghery, Noha A. Ahmed, Faris F. Aba Alkhayl, Al Mokhtar Lamsabhi   +5 more
wiley   +1 more source

Establishment of an efficient electroporation-based knock-in system in chicken primordial germ cells and a rapid method for positive cell selection. [PDF]

Poult Sci
Lv X, Wei Q, Sun J, Tan X, Gong W, Yao Z, Niu Y, Song J, Li B, Zuo Q.   +9 more
europepmc   +1 more source

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá, Ladislav Androvič, Marcela Filipová, Michal Pechar, Richard Laga   +4 more
wiley   +1 more source

An efficient electrotransformation method for three Bacillus species. [PDF]

Appl Microbiol Biotechnol
Quan W, Liu CL, Shi SX, Hao LJ, Wang HX, Liu ZG, Dong BZ, Zhou HY.   +7 more
europepmc   +1 more source