Results 241 to 250 of about 135,255 (300)

Human APOBEC3G suppresses homologous recombination and LIG4‐independent end joining in DNA double‐strand break repair

The FEBS Journal, EarlyView.
Chromosomal DNA double‐strand breaks (DSBs) are repaired by homologous recombination and nonhomologous end joining (NHEJ). Recent work has additionally established theta‐mediated end‐joining (TMEJ) as a mechanism for DSB joining. Cells lacking NHEJ and TMEJ can repair DSBs in a homology‐dependent manner.
Shinta Saito, Miori Murayama, Usaki Arai, Sekifumi Akatsu, Ami Yamamoto, Misaki Kadoguchi, Noritaka Adachi   +6 more
wiley   +1 more source

Functional and transcriptomic analyses in Neurospora crassa reveal a crucial role for the N‐glycoprotein deglycosylation process in fungal homeostasis

The FEBS Journal, EarlyView.
In Neurospora crassa, a cytosolic GH18 endo‐β‐n‐acetylglucosaminidase (ENGase) functions as an active deglycosylating enzyme. Deletion of this severely alters tolerance to multiple stress conditions and causes extensive transcriptomic reprogramming, including upregulation of a GH20 exo‐β‐n‐acetylhexosaminidase under ER stress, indicating that N. crassa
Anastasios Samaras, Tanim Jabid Hossain, Magnus Karlsson, Georgios Tzelepis   +3 more
wiley   +1 more source

Compound steep-pulse irreversible electroporation for prostate ablation in Beagle dogs: parameter evaluation and short-term safety. [PDF]

Front Urol
Chen Z, Zhao L, Zhang Z, Luo Z.
europepmc   +1 more source

A live‐cell autophagy reporter reveals reversible vacuolation in naked mole‐rat skin fibroblasts under lysosomal stress

The FEBS Journal, EarlyView.
A tandem fluorescent mCherry–EGFP–LC3 reporter enables live‐cell visualisation of autophagy–lysosome dynamics in naked mole‐rat skin fibroblasts. Chloroquine‐induced lysosomal stress promotes accumulation of neutral LC3‐positive compartments and triggers pronounced LC3‐associated vacuolation.
Fangze Tong, Mateo P. Hoare, Laura J. Grundy, Filomena Gallo, Karin H. Müller, Ewan St. John Smith, Janet R. Kumita   +6 more
wiley   +1 more source

Outcomes of Irreversible Electroporation for Treatment of Refractory Locally Advanced Pancreatic Cancer. [PDF]

J Vasc Interv Radiol
Azevedo R, Imagawa D, Rara M, Cho H, Cho K, Valerin J, Lee FC, Dayyani F, Fernando D, Abi-Jaoudeh N.   +9 more
europepmc   +1 more source

Gene Editing in <i>Chlamydomonas</i> Using the SCREAM Technique. [PDF]

Bio Protoc
Ross IL, Hankamer B.
europepmc   +1 more source

The future of PFA in cardiac ablation procedures. [PDF]

Europace
Andrade JG, Asirvatham SJ, Hocini M, Jacobsen PK, Reinsch N, Della Rocca DG, Sarkozy A, Tan N, Tri JA, Auricchio C, Raciti G, García-Sánchez T, Koruth J.   +12 more
europepmc   +1 more source

Custom bipolar electrode for bleomycin-based electrochemotherapy in patient-derived uveal melanoma <i>in ovo</i> and <i>ex vivo</i>. [PDF]

Front Cell Dev Biol
Anastasova R, Fiorentzis M, Yousefiboroujeni A, Gallo GP, Cadossi M, Dalbah S, Seitz B, Bechrakis NE, Tsimpaki T.   +8 more
europepmc   +1 more source