Durability of Pulsed Field Ablation Lesions: Current Understanding and Future Directions. [PDF]
Arrhythm Electrophysiol RevNeven K, Füting A, Hartl S, Reinsch N.
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Wellness-enhancing effects of the canine growth hormone releasing hormone therapy mediated by plasmid and electroporation in healthy old dogs [PDF]
Min‐Ok Ryu +9 more
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Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?
British Journal of Pharmacology, EarlyView.Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi +10 more
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Microfluidic electroporation for cellular analysis and delivery
, 2013 Tao Geng, Chang Lu
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PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes
British Journal of Pharmacology, EarlyView.Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier +9 more
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Electrochemotherapy in the Management of Vascular Malformations: An Updated Systematic Review. [PDF]
Clin PractMichailidis A +8 more
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Targeting Overexpressed IDO in Stromal Cells as a Potential Therapeutic Strategy in Multiple Myeloma
Cancer Science, EarlyView.IDO expression in stromal cells was upregulated by MM cells via the JAK–STAT1–NF‐κB–IRF1 signaling pathway. JAK inhibitor abolished IDO and IRF1 upregulation. ABSTRACT Stromal cells are an essential component of the tumor microenvironment (TME) in multiple myeloma (MM). Indoleamine 2,3‐dioxygenase 1 (IDO), an enzyme that metabolizes tryptophan (Trp) to
Toru Ebina +18 more
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Transfection of the free-living alga Chromera velia enables direct comparisons with its parasitic apicomplexan relative, Toxoplasma gondii. [PDF]
J Cell SciTengganu IF, Hu K.
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Clinical Genetics, EarlyView.CRISPR activation of NEB in fibroblasts, followed by RNA‐sequencing, documents spliceogenic effects of a NEB intronic variant. The assay enabled variant reclassification as likely pathogenic, providing molecular diagnosis in fetuses with Arthrogryposis multiplex congenita 6.
Doriana Misceo +7 more
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