Results 281 to 290 of about 192,083 (323)

CLEC18A interacts with sulfated glycosaminoglycans and controls clear cell renal cell carcinoma progression

The FEBS Journal, EarlyView.
CLEC18A is a previously poorly characterized C‐type lectin. We mapped the expression of CLEC18A to the proximal tubule of the kidney and found CLEC18A to interact with sulfated glycosaminoglycans on proteoglycans. Furthermore, we found that CLEC18A plays an important role in hindering the progression of clear cell renal cell carcinomas in humans and in
Gustav Jonsson, Maura Hofmann, Stefan Mereiter, Lauren Hartley‐Tassell, Masahiro Onji, Irma Sakic, Tiago Oliveira, David Hoffmann, Maria Novatchkova, Alexander Schleiffer, Josef M. Penninger   +10 more
wiley   +1 more source

Heterologous plastoquinone production using a newly identified O2‐dependent cyanobacterial hydroxylase

The FEBS Journal, EarlyView.
In this study, we confirm that PlqH is the hydroxylase operating in plastoquinone biosynthesis in photosynthetic cyanobacteria (Cyanobacteriia). Our phylogenetic analyses demonstrate that cyanobacterial PlqH homologues originated from hydroxylases involved in ubiquinone biosynthesis in bacteria. Plastoquinone production in Escherichia coli was achieved
Morgane Roger‐Margueritat, Margot Beltran, Juliette Schnoebelen, Laura Flandrin, Wafa Rezali, Eline Michel, Sophie S. Abby, Fabien Pierrel   +7 more
wiley   +1 more source

Targeted inhibition of <i>ELANE</i> expression using adenine base editing to treat severe congenital neutropenia. [PDF]

Mol Ther Methods Clin Dev
Findik B, Dannenmann B, Bernhard F, Kaufmann MM, Ammann S, Kandabarau S, Klimiankou M, Mauch F, Münzer P, Borst O, Klefenz I, Steinemann D, Lengerke C, Zeidler C, Cathomen T, Welte K, Nasri M, Skokowa J.   +17 more
europepmc   +1 more source

Development of Single Cell Electroporation Methods

, 2002
Frida Ryttsén
openalex   +1 more source

MAVS oligomerization drives a faster and more efficient antiviral signaling activation at peroxisomes compared to mitochondria

The FEBS Journal, EarlyView.
Cells rely on mitochondria and peroxisomes to trigger antiviral defenses via the protein MAVS. This manuscript demonstrates that the robust production of antiviral effectors resulting from MAVS activation at peroxisomes is faster than at mitochondria due to a swifter oligomerization of this protein at peroxisomal membranes. These results underscore the
Bruno Ramos, Jéssica Sarabando, Mariana Marques, Jonathan C. Kagan, Daniela Ribeiro   +4 more
wiley   +1 more source

Complexity and Perplexity of Pulsed Field Ablation: An Engineering Perspective. [PDF]

Arrhythm Electrophysiol Rev
Kos B, Reberšek M, Miklavčič D.
europepmc   +1 more source

Signal Transducer and Activator of Transcription (STAT) Proteins Regulate Mucosal‐Associated Invariant T (MAIT) Cell Function

Immunology, EarlyView.
Integrated transcriptomic, proteomic and flow cytometry analyses reveal that STAT1 negatively regulates MAIT cell effector and glycolytic functions, while STAT3, STAT5 and HIF1α act as positive modulators. Targeting these pathways may offer new strategies to restore MAIT cell function in immune dysregulation and cancer.
Olivia J. Cheng, Eimear K. Ryan, Michael Bennett, Christy Clutter, Jackson G. Cacioppo, Jeffrey Aubé, Andy E. Hogan, Daniel T. Leung   +7 more
wiley   +1 more source

Electroporation for the Treatment of Pancreatic Ductal Adenocarcinoma: A Systematic Review of Preclinical and Clinical Studies. [PDF]

Clin Transl Gastroenterol
Marcellier G, Le Berre T, Rivallin P, Frenea-Robin M, Prat F.   +4 more
europepmc   +1 more source

Proteolysis Targeting Chimera Loaded Extracellular Vesicles for Developing Triple Negative Breast Cancer Treatment. [PDF]

J Extracell Vesicles
Erwin N, De U, Xiao Y, Wang L, Maharjan CK, Pan X, Zuo D, Awasthee N, Zheng G, Liao D, Zhang W, He M.   +11 more
europepmc   +1 more source

A characterization of the reversibly electroporated penumbra during irreversible electroporation

Rasmus Virenfeldt Flak, Jonatan Riber Granborg, Christian Janfelt, Martin Skovmos Nielsen, Benedict Kjærgaard, Ole Thorlacius‐Ussing   +5 more
openalex   +1 more source