Results 31 to 40 of about 19,050 (176)

Diabetic rats with high levels of endogenous dopamine do not show retinal vascular pathology

Frontiers in Neuroscience, 2023
PurposeLimited research exists on the time course of long-term retinal and cerebral deficits in diabetic rodents. Previously, we examined short term (4–8 weeks) deficits in the Goto-Kakizaki (GK) rat model of Type II diabetes.
Rachael S. Allen, Rachael S. Allen, Cara T. Khayat, Andrew J. Feola, Andrew J. Feola, Andrew J. Feola, Alice S. Win, Alice S. Win, Allison R. Grubman, Allison R. Grubman, Kyle C. Chesler, Kyle C. Chesler, Li He, Li He, Jendayi A. Dixon, Timothy S. Kern, Timothy S. Kern, Timothy S. Kern, P. Michael Iuvone, P. Michael Iuvone, Peter M. Thule, Machelle T. Pardue, Machelle T. Pardue, Machelle T. Pardue   +23 more
doaj   +1 more source

Pattern electroretinogram in glaucoma

, 2006
PURPOSE OF REVIEWSeveral studies have shown that the pattern electroretinogram, a direct, objective method of measuring retinal ganglion cell function, is altered early in ocular hypertension and glaucoma.
Porciatti, Vittorio, Ventura, Lori
core   +1 more source

Stratification of the Extent of Visual Impairment Identifies Sex-Specific Degenerative Changes in Retinal Structure and Function during Aging

Journal of Integrative Neuroscience
Background: Initial manifestations of neurodegenerative ocular conditions, including age-related macular degeneration (AMD) and glaucoma, often remain undetected in the early stages and can begin after the age of 50 years with the ...
Genea Edwards, Sean M. Riordan, Caitlin Buchholz, Marc Mardelli, Carlyn P. Euritt, Rodrigo Perez-Magnelli, Ariej Rafiq, Avery Engelmeyer, Peter Koulen   +8 more
doaj   +1 more source

Аutosomal Dominant Oculodental-Digital Dysplasia with Mutation in Gene GJA1 (Clinical Case)

Oftalʹmologiâ, 2021
The purpose: to describe clinical cases of oculodental-digital dysplasia (ODDD, OMIM #164200) with mutation in GJA1 (OMIM 121014) with molecular genetic verification of the diagnosis.Methods. The article describes the clinical case of oculodental-digital
I. V. Zolnikova, V. V. Kadyshev, A. V. Marakhonov, S. I. Kutsev, R. A. Zinchenko   +4 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Early ophthalmic findings in joubert syndrome

Journal of the Egyptian Ophthalmological Society, 2017
Aim The aim of this study was to determine the early ophthalmic and electrophysiological features of Joubert syndrome (JS) in young Egyptian children and compare them with other studies.
Amira A Abdelazeem, Olfat A Hassanin, Amal A Elgohary, Maha S Zaki, Amany H Galal, Joseph G Gleeson   +5 more
doaj   +1 more source

Retina‐Inspired Bi‐Based Terahertz Photonic Neuromorphic Devices

Advanced Science, EarlyView.
Combined with effective band alignment and substrate engineering, bismuth materials are introduced to form terahertz photonic bio‐inspired devices with picosecond short‐term plasticity to enable multi‐scene visual perception. Thus obtained hardware through the terahertz optical neural network (THz‐ONN) demonstrates high recognition accuracy, providing ...
Pujing Zhang, Donggang Xie, Longyu Shi, Mengyuan Wang, Huiwen Shi, Yu Wu, Menglei Li, Guangwei She, Peijie Wang, Wensheng Shi, Cunlin Zhang, Kuijuan Jin, Guozhen Yang, Qingli Zhou, Chen Ge   +14 more
wiley   +1 more source

Development of a novel knockout model of retinitis pigmentosa using Pde6b-knockout Long–Evans rats

Frontiers in Medicine, 2022
Although rats with melanin-pigmentated retinal pigment epithelial (RPE) cells are physiologically more appropriate models for human eye research than their albino counterparts, reliable models from the former strain are not available to study retinal ...
Jee Myung Yang, Jee Myung Yang, Bora Kim, Jiehoon Kwak, Min Kyung Lee, Jeong Hoon Kim, In-Jeoung Baek, In-Jeoung Baek, Young Hoon Sung, Young Hoon Sung, Joo Yong Lee   +10 more
doaj   +1 more source

Modulation of Presynaptic Inhibitory Retinal Circuits for Retinal Ganglion Cell Neuroprotection in Glaucoma

Advanced Science, EarlyView.
Ocular hypertension induces early hyperactivity in inner retinal inhibitory circuitry before substantial retinal ganglion cell loss. Sustained pharmacological inhibition of GABAergic/glycinergic neurotransmission and Vgat‐targeted Lin28 expression suppress this hyperactivity and improve RGC survival without reducing intraocular pressure. These findings
Eunji Hong, Chen Lin, Wenjie Long, Ian Kim, Mengwen Xiong, Zuer Wu, Siyuan Rao, Qianbin Wang   +7 more
wiley   +1 more source

Electroretinogram (ERG) improvement after OAC.

, 2018
Electroretinogram (ERG) improvement after OAC.
David H. Abramson (307429), Jasmine H. Francis (307427), Megan A. Rowlands (5146880), Ariana Levin (5146877), Ijah Mondesire-Crump (2816995), Audrey Mauguen (241088), Scott E. Brodie (307428), Y. Pierre Gobin (307424), Ira J. Dunkel (307425)   +8 more
core   +1 more source