Results 41 to 50 of about 19,050 (176)

A Rare Form of Microcephalic Primordial Dwarfism due to NSMCE2 Deficiency (Seckel Syndrome Type 10): A Report of Macular Involvement

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic variants in NSMCE2 (MMS21), which encodes the SUMO E3 ligase subunit of the SMC5/6 chromatin‐maintenance complex, have recently been implicated in microcephalic primordial dwarfism (MPD), corresponding to Seckel syndrome type 10 (OMIM #617246).
Cristina Peduto, Céline Huber, Clément Paya, Isabelle Audo, Nathalie Boddaert, Valérie Cormier‐Daire   +5 more
wiley   +1 more source

A spatially specified systems pharmacology therapy for axonal recovery after injury

Frontiers in Pharmacology, 2023
There are no known drugs or drug combinations that promote substantial central nervous system axonal regeneration after injury. We used systems pharmacology approaches to model pathways underlying axonal growth and identify a four-drug combination that ...
Mustafa M. Siddiq, Nicholas P. Johnson, Nicholas P. Johnson, Nicholas P. Johnson, Yana Zorina, Arjun Singh Yadaw, Carlos A. Toro, Carlos A. Toro, Jens Hansen, Vera Rabinovich, Sarah M. Gregorich, Yuguang Xiong, Rosa E. Tolentino, Sari S. Hannila, Ehud Kaplan, Ehud Kaplan, Robert D. Blitzer, Marie T. Filbin, Christopher P. Cardozo, Christopher P. Cardozo, Christopher P. Cardozo, Christopher L. Passaglia, Ravi Iyengar   +22 more
doaj   +1 more source

Monitoring and assessment for obstructive sleep apnea

FlexMat, EarlyView.
This review systematically classifies Obstructive Sleep Apnea (OSA) monitoring indicators into three categories: physical, biochemical, and electrophysiological indicators, and lists several methods for each category. Abstract Obstructive sleep apnea (OSA) is a common chronic sleep‐disordered breathing disease characterized by recurrent upper airway ...
Yaowen Xu, Feifei Lin, Shujiao Chen, Zhen You, Shujing Zhu, Weiwei Zhao, Qiang Zhao   +6 more
wiley   +1 more source

Electroretinography and OCT angiography of the retina and optic nerve in retinitis pigmentosa

Российский офтальмологический журнал, 2018
OCT angiography, an innovative noninvasive technique, allows a comprehensive assessment of eye vessels, separately for the choroidal and the retinal vasculature.
V. . Zolnikova, D. V. Levina, T. D. Okhotsimskaya, V. A. Fadeeva, I. V. Egorova, E. V. Rogatina, E. A. Eremeeva, O. N. Demenkova, S. Yu. Rogova   +8 more
doaj   +1 more source

Artificial intelligence, equity, and pediatric neurodevelopmental disorders: A scoping review of clinical practice applications

Pediatric Investigation, EarlyView.
Artificial intelligence (AI) is being explored to support diagnosis and care for pediatric neurodevelopmental disorders, yet most tools remain in early stages of development. This scoping review identifies limited external validation, narrow population representation, and sparse equity considerations, underscoring the need for inclusive, clinically ...
Florida Uzoaru, Obinna O. Oleribe, Ucheoma Nwaozuru, Parichart Sabado   +3 more
wiley   +1 more source

Retinal dystrophies simulating geographic atrophy: A diagnostic challenge

Acta Ophthalmologica, EarlyView.
Abstract Geographic atrophy (GA) is the chronic loss of retinal pigment epithelium, photoreceptors and choriocapillaris, marking the dry late stage of age‐related macular degeneration (AMD). GA prevalence is expected to rise in the upcoming decades. Advanced GA leads to central scotomas, reducing visual acuity and quality of life, potentially resulting
Johanna M. Colijn, Frank G. Holz, Jeroen Pas, Carel Hoyng   +3 more
wiley   +1 more source

Effects of Different Degrees of Cataract on the Multifocal Electroretinogram

, 2004
Aim. To study the effect of different degrees of nuclear cataract on the multifocal electroretinogram (mfERG). Methods. mfERGs were recorded from 30 elderly subjects with very mild, mild, or moderate nuclear cataracts using a VERIS System (version 4.1 ...
Chan, H, Brown, B, H Chan, B Brown, Yap, M, M Yap, Tam, W-K, Brown, Brian, W-K Tam, Yap, Maurice, Tam, WK   +10 more
core   +1 more source

Differences in the Effects of Pentobarbital Anesthetic and Combination of Medetomidine Hydrochloride, Midazolam, and Butorphanol Tartrate Anesthetic on Electroretinogram in Spontaneously Diabetic Torii Fatty Rats

Biomedicine Hub, 2022
Purpose: The aim of this study was to investigate the effects of different anesthetic agents on electroretinograms (ERGs) in Spontaneously Diabetic Torii fatty rats (SDT fatty rats).
Tetsuya Hasegawa, Rina Takagi, Yoshiaki Tanaka, Takeshi Ohta, Masami Shinohara, Yasushi Kageyama, Tomohiko Sasase, Shin-ichi Muramatsu, Toshikatsu Kaburaki, Akihiro Kakehashi   +9 more
doaj   +1 more source

Inter‐eye microvascular asymmetry across stages of diabetic retinopathy: An OCT angiography study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate inter‐eye asymmetry in macular microvascular parameters across different stages of diabetic retinopathy (DR) using OCT angiography, and to explore the associations with clinical factors. Methods This cross sectional study included 442 eyes of 221 patients with diabetes mellitus type 2. Central subfield thickness (CST), area
Stela Vujosevic, Sema Tamer Kaderli, Gabriele Piccoli, Elena Tagliabue, Camilla Alovisi, Vanda Bucceri, Emanuele Torti, Elisa Marenzi, Dogukan Ozen, Livio Luzi, Paolo Nucci   +10 more
wiley   +1 more source

Spectral sensitivity of the compound eyes of Anomala corpulenta motschulsky (Coleoptera: Scarabaeoidea)

Journal of Integrative Agriculture, 2015
The scarab beetle, Anomala corpulenta Motschulsky (Coleoptera: Scarabaeoidea), is a widespread and destructive pest in China. Vision is one of the most important means of acquiring information about the external environment. In order to contribute to the
Yue-li JIANG, Yu-yuan GUO, Yu-qing WU, Tong LI, Yun DUAN, Jin MIAO, Zhong-jun GONG, Zhi-juan HUANG   +7 more
doaj   +1 more source