MK-212 precipitates seizure-induced death in amygdala-kindled mice via a non-5-HT<sub>2C</sub> receptor-mediated mechanism. [PDF]
Joyal KG, Boodhoo NA, Buchanan GF.
europepmc +1 more source
ABSTRACT Cognitive behavioral therapy (CBT) is a well‐established, evidence‐based treatment for common mental disorders such as depression, anxiety disorders, and obsessive‐compulsive disorder (OCD). However, treatment outcomes vary widely, and a substantial proportion of patients do not achieve sufficient improvement.
Julia Bäckman +41 more
wiley +1 more source
Sleep Deprivation and Neuronal Hyperexcitation Share Transcriptomic Signatures
This study demonstrated that sleep deprivation induces transcriptomic changes in mice and rats similar to those observed in various models of neuronal hyperexcitation. These findings suggest a potential link between sleep deprivation and neuropsychiatric disorders.
Markos Michail Chatzigiannis +2 more
wiley +1 more source
Galvanostatic Electroshock Synthesis of Low Loading Au-Pt Nanoalloys Onto Gas Diffusion Electrodes as Multifunctional Electrocatalysts for a Glycerol-Fed Electrolyzer. [PDF]
Hagheh Kavousi Z +7 more
europepmc +1 more source
ABSTRACT Wind tunnel experiments are a key element of fluid mechanics education, enabling students to connect theoretical knowledge with practical observations. Despite their pedagogical value, traditional wind tunnel laboratories often lack outcome orientation, rely on prescriptive procedures, and provide limited opportunities for conceptual ...
Nils Kaufhold, Konrad Boettcher
wiley +1 more source
Seizure Susceptibility in <i>Drosophila melanogaster</i> is Reduced with CBD and <i>Z. jujube</i> treatment. [PDF]
Kubitz Z +7 more
europepmc +1 more source
ABSTRACT Introduction Major depressive disorder (MDD) affects 11%–19% of adolescents globally. Early treatment is vital, but the risk of relapse is high, with 46% relapse within 5 years, which threatens a chronic course. Hence, better solutions are needed.
Lidija Rakic +8 more
wiley +1 more source
Design, synthesis, and in vitro, in vivo, and in silico evaluation of novel substituted 1,3,4-thiadiazole derivatives as anticonvulsant agents. [PDF]
Anthwal T, Pant S, Rana P, Nain S.
europepmc +1 more source
ToxIR: an accurate RNA-seq pipeline for high-precision toxin transcriptome profiling, validated in odontobuthus doriae venom glands. [PDF]
Ebadi M, Soorki MN.
europepmc +1 more source

