Results 41 to 50 of about 16,832 (328)

Reprogramming the Myocardial Infarction Conductive Microenvironment with Superconductive Ionic Patch for Cardiac Function Repair

Advanced Science, EarlyView.
A super‐conductive ionic patch reprograms the post‐infarction microenvironment by enabling stable ionic migration and electrical signal transmission within damaged myocardium. The patch rapidly adheres to cardiac tissue, enhances conduction velocity, suppresses excitation‐contraction decoupling, and promotes structural and functional cardiac repair in ...
Changyong Wang, Zhuang Zhang, Qi Yin, Changgeng Xu, Linlin Liang, Siwei Li, Yuwei Zhao, Chunlan Wang, Jin Zhou   +8 more
wiley   +1 more source

Screening study of new thiazolidinone derivatives for anticonvulsant activity

Zaporožskij Medicinskij Žurnal, 2020
The search for new antiepileptic drugs that would have greater margins of safety and fewer adverse effects is relevant. Thiazolidinone are a promising class for the development of new anticonvulsants. Aim.
M. V. Mishchenko , S. Yu. Shtrygol, R. B. Lesyk, A. V. Lozynskyi, S. M. Holota   +4 more
doaj   +1 more source

Determinación de factores influyentes sobre una respuesta en un dominio poco estructurado [PDF]

, 2001
This report focuses on results obtained from a classification technique applied to time series data in a medical ill-structured The statistical analysis and classification --in ill-structured-- of such data are often inadequate because of the ...
Gibert, Karina, Rodas Osollo, Jorge Enrique, Rojo, Emilio   +2 more
core   +1 more source

Interchangeable punishments during aversive conditioning in Drosophila [PDF]

, 2013
Using Drosophila melanogaster larvae we asked whether distinct aversive stimuli have a common neuralrepresentation during associative learning. We tested the interchangeability of heat shock and electroshock punishments when used within a single ...
Atkinson, N. S., Chuang, T., Hooten, J., Khurana, S., Nguyen, A., Robinson, B. G., Young, M., Yu, J.   +7 more
core   +1 more source

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

NOVEL PYRIMIDINE DERIVATIVES WITH ANTICONVULSANT AND PSYCHOTROPIC EFFECTS

Эпилепсия и пароксизмальные состояния, 2017
Objective: to study the anticonvulsant and psychotropic effects of novel benzothienopyrimidine derivatives and rationalize their use for medical practice.Materials and methods. The anticonvulsant effects were studied by using the models of murine seizure
R. G. Paronikyan
doaj   +1 more source

Beyond Cocrystals: Hierarchical Functional Assemblies via Noncovalent Synthesis

Advanced Science, EarlyView.
Non‐covalent interactions (NCIs) drive the formation of organic cocrystals with diverse structures and tunable optoelectronic properties. This review explores the essential factors governing these properties, highlighting how the sequential nucleation of cocrystals leads to the self‐assembly of organic hierarchical structures (OHSs).
Ya‐Nan Zhu, Jin Feng, Ying‐Xin Ma, Hong‐Tao Lin, Li‐Wei Xie, Qi‐Liang Peng, Xue‐Dong Wang   +6 more
wiley   +1 more source

Solution‐Shearing of Highly Smooth Ion‐Gel Thin Films: Facilitating the Deposition of Organic Semiconductors for Ion‐Gated Organic Field Effect Transistors

Advanced Electronic Materials, Volume 11, Issue 6, May 2025.
A straightforward method is introduced to produce ion‐gel films with very low surface roughness by employing a solution‐shearing coating process. These ion‐gel films permit the growth of crystalline thin films of various small molecule organic semiconductor molecules directly on top of the ion‐gel layer, thereby enabling “inverted” small molecule ...
Jonathan Perez Andrade, Angelika Wrzesińska‐Lashkova, Anupam Prasoon, Felix Talnack, Katherina Haase, Bernd Büchner, Xinliang Feng, Yana Vaynzof, Mike Hambsch, Yulia Krupskaya, Stefan C. B. Mannsfeld   +10 more
wiley   +1 more source

Anticonvulsant activity of atorvastatin against seizure induced by pentylenetetrazole and maximal electroshock in mice [PDF]

Trends in Pharmaceutical Sciences, 2015
Statins are inhibitors of HMG-CoA reductase and inhibit cellular synthesis of cholesterol and isoprenoids. Studies have previously demonstrated the anti-inflammatory and vasoprotective effects of statins on cultured brain cells (astrocytes and microglia)
Mohammad Khoshnoud, Nader Tanideh, Samaneh Namdarian   +2 more
doaj   +3 more sources

KIND OF ACTIVITY ANTIABSENCE IN MICE PRODUCED BY THE METHANOLIC EXTRACT FROM Cecropia Membranacea Trécul

Vitae, 2009
The methanolic extract obtained from Cecropia membranacea Trécul (0,5 g/kg v.o.) administered to mice albinos ICR, elicits antiseizure activity (73% of protection) in mice exposed to pentilentetrazol (PTZ, 80 mg/kg, sc.), chemical model of absence crisis.
Dúmar A. JARAMILLO H., Javier RINCÓN V., Mario F. GUERRERO P.   +2 more
doaj