Effects Of 4-thiazolidinone Derivatives Les-2658 And Les-1205 On Sleep - Wakefulness Cycle In Kindled Rats [PDF]
, 2017 The research is dedicated to in-depth study of neurotrophic and antiepileptic properties of original potential anticonvulsant agents from 4-thiazolidinones – LES-2658 (5-(3-nitro-benzylidene)-2-(thiazol-2-ylimino)-thiazolidin-4-one) and LES-1205 ([2,4 ...
Lesyk, R. (Roman) +2 more
core +2 more sources
Advanced Materials, EarlyView.A highly‐emissive organic photovoltaic employs donor–acceptor pairs with alternately localized frontier molecular orbitals, preserving high triplet energies and small reorganization energies to suppress non‐radiative recombination. As a result, it exhibits a high open‐circuit voltage approaching the Shockley–Queisser limit and a high ...
Qing‐Jun Shui +7 more
wiley +1 more source
Эпилепсия и пароксизмальные состояния, 2020 Aim – experimental evaluation of the antiepileptic activity of a new amide derivative of valproic acid and 1,3,4-thiadiazole.Materials and Methods: The antiepileptic activity of valprazolamide (N- (5-ethyl-1,3,4-thiadiazol-2-yl) -2-propylpentanamide) was
A. S. Malygin
doaj +1 more source
Degradation Mechanisms in PEM Water Electrolysis: Diagnosis and Impact
Advanced Materials Technologies, EarlyView.This review provides an analysis of degradation mechanisms in proton electrolyte membrane water electrolyzers (PEMWE), focusing on all key components. It discusses diagnostic and measurement techniques for evaluating degradation, less‐studied mechanisms, and an expert survey.
Annik Bernhardt +11 more
wiley +1 more source
Efektivitas antiepilepsi ekstrak pegagan (Centella asiatica (L.) Urb. dalam etanol, diklorometana dan heksan pada mencit putih jantan menggunakan Metode MES (Maximum Electroshock Seizure) [PDF]
, 2008 Epilepsi adalah gangguan neurologik dengan insiden cukup tinggi dan selama ini terapi epilepsi dengan pengobatan sintetik dalam jangka waktu lama mengakibatkan timbulnya efek samping yang besar bagi penderita. Untuk itu diperlukan suatu alternatif dalam
., Ivana +4 more
core
Evaluation of the central activity of the ethanolic extract of Acosmium subelegans (Mohlenbr) in mice [PDF]
, 2002 The ethanolic extract (EE) of Acosmium subelegans (Mohlenbr) Yakovl (perobinha-do-campo) was tested to behavioral paradigms in mice to investigate its putative central depressant effect.
Lapa, Antonio José +2 more
core +2 more sources
Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management
Advanced Science, EarlyView.ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak +9 more
wiley +1 more source
Screening study of new thiazolidinone derivatives for anticonvulsant activity
Zaporožskij Medicinskij Žurnal, 2020 The search for new antiepileptic drugs that would have greater margins of safety and fewer adverse effects is relevant. Thiazolidinone are a promising class for the development of new anticonvulsants. Aim.
M. V. Mishchenko +4 more
doaj +1 more source
Anticonvulsant Activity of Viola tricolor against Seizures Induced by Pentylenetetrazol and Maximal Electroshock in Mice [PDF]
Iranian Journal of Medical Sciences, 2019 Background: Recently, there has been much more interest in the use of medicinal plants in search of novel therapies for human neurodegenerative diseases such as epilepsy. In the present study, we investigated the anticonvulsant effects of Viola tricolor (
Vafa Baradaran Rahimi +4 more
doaj +1 more source
How Can Network-Pharmacology Contribute to Antiepileptic Drug Development? [PDF]
, 2014 Network-pharmacology is a field of pharmacology emerging from the observation that most clinical drugs have multiple targets, contrasting with the previously dominant magic bullet paradigm which proposed the search of exquisitely selective drugs. What is
Di Ianni, Mauricio Emiliano +1 more
core +1 more source