Results 51 to 60 of about 5,119 (263)
Anticonvulsant effects of thymoquinone, the major component of Nigella sativa seeds in mice
Journal of Medicinal Plants, 2003 The anticonvulsant effect of thymoquinone, the major component of nigella sativa seeds, were investigated using pentylenetetrazole (PTZ) and Maximal electroshock test (MES), as petit mal and grand mal epilepsy models in mice, respectively.
S Parvardeh, M Fatehi, H Hosseinzadeh
doaj
Do endogenous opioids and nitric oxide participate in the anticonvulsant action of dipyrone?
Brazilian Journal of Medical and Biological Research, 2003 It was previously reported that systemic administration of dipyrone inhibited the tonic component of generalized tonic-clonic seizures in both the electroshock and the audiogenic seizure models.
G.M.L. Reis +3 more
doaj +1 more source
The Anatomical Record, EarlyView.Abstract The study of morphological evolution is fundamentally tied to ontogeny, yet studies of these heterochronic processes in the fossil record are rare. Fossils belonging to an ontogenetic series are difficult to assign to an ontogenetic stage due to inconsistent proxies for skeletal ages, challenging to taxonomically assign due to morphological ...
Erika R. Goldsmith, Michelle R. Stocker
wiley +1 more source
Redescription of the Triassic cynodont Cistecynodon parvus and reassessment of its phylogeny
The Anatomical Record, EarlyView.Abstract Cynodontia is an important subclade of Therapsida that first occurred in the late Permian. It includes extinct subclades which are the non‐mammaliaform cynodonts and Mammaliaformes, with the latter ultimately giving rise to crown mammals. The systematics of non‐mammaliaform cynodonts has been extensively studied and is relatively well‐resolved,
Erin S. Lund +4 more
wiley +1 more source
Anticonvulsant activity of bioflavonoid gossypin [PDF]
Bangladesh Journal of Pharmacology, 2009 The anticonvulsant activity of gossypin was investigated by studying the effects on seizures induced by pentelentetrazole, strychnine and maximal electroshock convulsive methods in mice.
Srinivasan Duraisamy +2 more
doaj
The Anatomical Record, EarlyView.Abstract Prozostrodon brasiliensis, a probainognathian cynodont of the clade Prozostrodontia, is recognized as a key taxon for understanding the origin of Mammaliaformes and mammals. Despite detailed investigations of its cranial anatomy, the postcranial skeleton has received comparatively less attention.
Iasmim M. Michelotti +4 more
wiley +1 more source
Design, synthesis and pharmacological profile of (−)-verbenone hydrazones
Open Chemistry, 2020 A series of novel (−)-verbenone hydrazones was designed and synthesized via condensation of terpenoid with hydrazides derived from phenoxyacetic acid.
Nesterkina Mariia +2 more
doaj +1 more source
Neurosteroids and Seizure Activity
Frontiers in Endocrinology, 2020 Still circa 25% to 30% of patients with epilepsy cannot be efficiently controlled with available antiepileptic drugs so newer pharmacological treatment options have been continuously searched for.
Barbara Miziak +2 more
doaj +1 more source
Anatomical Sciences Education, EarlyView.Abstract Human body prosection practices are a crucial educational tool for learning anatomy. However, the first exposure to donors' material can cause anxiety, which may affect students' learning experiences and emotional adjustment. This observational study aimed to analyze anxiety levels (state and trait) before and after a prosection session in ...
Mónica Grande‐Alonso +8 more
wiley +1 more source
Autism Research, EarlyView.ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin +3 more
wiley +1 more source