Results 71 to 80 of about 22,824 (329)

Zur Einführung der „Schocktherapien" und Leukotomie in Deutschland [PDF]

open access: yes, 2020
Die Geschichte der „Schocktherapien“ und Leukotomie in Deutschland war lange ein vernachlässigtes Kapitel der Psychiatriegeschichte. Vorurteile behinderten über Jahre hinweg eine detaillierte Aufarbeitung.
Rzesnitzek, Lara
core   +1 more source

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

open access: yesCytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas   +5 more
wiley   +1 more source

Is there a potential of misuse for Magnolia officinalis compounds/metabolites? [PDF]

open access: yes, 2017
© 2017 John Wiley & Sons, Ltd.Objective: Magnolia bark contains magnolol, metabolized to tetrahydromagnolol and honokiol, with both GABA-ergic/cannabimimetic activities, hence of possible attraction to vulnerable individuals/recreational misusers ...
Alexeev   +32 more
core   +3 more sources

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

open access: yesCytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius   +6 more
wiley   +1 more source

Electroshock Induced Seizures in Adult C. elegans

open access: yesBio-Protocol, 2017
The nematode Caenorhabditis elegans is a useful model organism for dissecting molecular mechanisms of neurological diseases. While hermaphrodite C. elegans contains only 302 neurons, the conserved homologous neurotransmitters, simpler neuronal circuitry,
Monica Risley   +2 more
doaj   +1 more source

Capturing Electrochemically Galvanic Exchange Events between Silver and Gold in Nonequilibrium and Equilibrium Realms

open access: yesChemistry–Methods, EarlyView.
A new methodology is presented to study the kinetics of the galvanic replacement reaction between silver and gold, allowing, for the first time to our knowledge, real‐time monitoring of the dynamics of this redox reaction by quantifying the main driving force, that is, the time‐ and concentration‐dependent redox potential, which cannot be captured by ...
Bonito Aristide Karamoko   +2 more
wiley   +1 more source

Compound 48/80, a histamine-depleting agent, blocks the protective effect of morphine against electroconvulsive shock in mice

open access: yesBrazilian Journal of Medical and Biological Research, 2000
We have shown that morphine has an anticonvulsive effect against maximal electroconvulsive shock (MES) in mice, and this effect is antagonized by histamine H1-receptor antagonists.
Karadag C.H.   +4 more
doaj  

Pharmacokinetic-pharmacodynamic influence of N-palmitoylethanolamine, arachidonyl-2′-chloroethylamide and WIN 55,212-2 on the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice [PDF]

open access: yes, 2016
We evaluated the effects of ACEA (selective cannabinoid (CB)1 receptor agonist), WIN 55,212-2 mesylate (WIN; non-selective CB1 and CB2 receptor agonist) and N-palmitoylethanolamine (PEA; an endogenous fatty acid of ethanolamide) in DBA/2 mice, a genetic ...
AVAGLIANO, CARMEN   +7 more
core   +1 more source

Creativity, collaboration and conformity: Curriculum making and teacher motivation

open access: yesThe Curriculum Journal, EarlyView.
Abstract There is a teacher recruitment and retention crisis in England. There is a particular challenge in recruiting physical science teachers, with government targets for recruitment being missed for the last 10 years and a high proportion of physical science teachers leaving early in their careers.
Victoria Wong
wiley   +1 more source

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