Results 81 to 90 of about 5,136 (262)

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development

Epilepsia, EarlyView.
Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Anticonvulsant activity of atorvastatin against seizure induced by pentylenetetrazole and maximal electroshock in mice [PDF]

Trends in Pharmaceutical Sciences, 2015
Statins are inhibitors of HMG-CoA reductase and inhibit cellular synthesis of cholesterol and isoprenoids. Studies have previously demonstrated the anti-inflammatory and vasoprotective effects of statins on cultured brain cells (astrocytes and microglia)
Mohammad Khoshnoud, Nader Tanideh, Samaneh Namdarian   +2 more
doaj  

Antiseizure potency and neurotoxicity of the enantiomers of fenfluramine and norfenfluramine in rats and correlations with their concentrations in plasma and brain

Epilepsia, EarlyView.
Abstract Objective Based on the evidence that fenfluramine‐induced anorexia, weight loss, and cardiovascular toxicity are primarily mediated by the d‐enantiomers of fenfluramine and its metabolite norfenfluramine, we investigated pharmacokinetic/pharmacodynamic correlations for the active enantiomers of fenfluramine and norfenfluramine in the rat ...
Yara Sheeni, Dinorah Barasch, Tawfeeq Shekh‐Ahmad, Emilio Perucca, Meir Bialer   +4 more
wiley   +1 more source

Cumulative electroconvulsive therapy sessions and focal epilepsy: A nationwide cohort study in Japan

Epilepsia Open, EarlyView.
Abstract Objective Electroconvulsive therapy (ECT) is widely used for severe psychiatric disorders, yet concerns remain regarding possible epileptogenic effects associated with prolonged or repeated exposure. We examined the association between cumulative ECT sessions and focal epilepsy in a nationwide Japanese cohort.
Masahiro Hata, Yuki Miyazaki, Hisaki Omori, Shun Takahashi, Manabu Ikeda   +4 more
wiley   +1 more source

Mortality and Morbidity Rate among ECT Patients; A Report from an Academic Hospital

روانشناسی و روانپزشکی شناخت
Introduction: Electroshock therapy is an effective treatment method for patients who are resistant to drug treatment or need an emergence response. Aim: The aim of this study was to investigate the mortality rate and complications caused by electroshock
Ali Pourramzani, Soheil Soltanipour, Gelareh Biazar, Mohadese Ahmadi, Shabnam Nikravesh Bishegahy, Batul Montazery, Samira Mirzababaei   +6 more
doaj  

Pregnancy‐ and lactation‐associated osteoporosis: A position statement of the IAPM, IOF, ECTS, ESCEO, IMS, and EMAS

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pregnancy‐ and lactation‐associated osteoporosis (PLO) is a syndrome characterized by fragility fractures (most commonly vertebral, often multiple) occurring in late pregnancy or the early postpartum period. This position statement summarizes the current knowledge of PLO, and the recommended procedure for assessment, diagnosis and treatment ...
Peyman Hadji, Apostolos Athanasiadis, Maria‐Luisa Brandi, Marlene Chakhtoura, Manju Chandran, Frank Chervenak, Amos Grünebaum, Irene Lambrinoudaki, Willem F. Lems, Apostolos M. Mamopoulos, Eugene McCloskey, Rossella E. Nappi, Jessica Pepe, Jean‐Yves Reginster, René Rizzoli, Petra Stute, Şansın Tuzun, Amanda J. Vincent, Maria Belen Zanchetta, M. Carola Zillikens, Ioannis Kyvernitakis   +20 more
wiley   +1 more source

Diminished: Canadian Women's Experiences of Electroshock

Atlantis, 2015
“Diminished” is the result of a two-year feminist inquiry into the gendered experience of electroconvulsive therapy (ECT) in Canada. This paper focuses on seven women’s experiences with electroshock and how it affected their lives.
Cheryl Cheryl van van Daalen-Smith
doaj  

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

Journal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik, Orsolya Balázs, Róbert G Vida, Balázs Z Zsidó, Csaba Hetényi, Kateřina Valentová, Miklós Poór   +6 more
wiley   +1 more source

Sentio Bone‐Conduction Implant: Early Outcomes in Patients With Conductive or Mixed Hearing Loss

The Laryngoscope, EarlyView.
This study evaluated the initial clinical outcomes, safety, and audiological performance of the Sentio active bone‐conduction implant in patients with conductive or mixed hearing loss. Implantation resulted in significant improvements in hearing thresholds, speech recognition, speech perception in noise, and patient‐reported hearing benefit, with no ...
Katarzyna Beata Cywka, Piotr Henryk Skarzynski, Monika Baczyk, Magda Balwicka‐Kowalczyk, Henryk Skarzynski   +4 more
wiley   +1 more source

Establishing Monthly Benchmarks for Erosion Control and Vegetation Restoration Targets Across the Loess Plateau

Land Degradation &Development, EarlyView.
ABSTRACT Establishing scientifically grounded soil erosion control targets and feasible vegetation restoration strategies is crucial for high quality development of the Chinese Loess Plateau which is severely affected by soil erosion. Currently, the commonly used tolerable soil loss (TSL) is inadequate for addressing the spatial heterogeneity in ...
Ye Wang, Haijing Shi, Xihua Yang, Rui Li, Hongming Zhang, Jiaqiong Zhang, Wenyi Sun, Yangyang Liu, Qinggaozi Zhu, Guang Yang   +9 more
wiley   +1 more source