Determination of the endogenous phosphorylation state of B‐50/GAP‐43 and neurogranin in different brain regions by electrospray mass spectrometry [PDF]
Mónica Di Luca+6 more
openalex +1 more source
This study uncovers a novel mechanism in which p300‑catalyzed lactylation of HMGB1 triggers nuclear export of the HMGB1‐TIAR complex, driving TIAR‐dependent SGs formation in the cytoplasm. Mass spectrometry and mutagenesis reveals that K177 lactylation is essential for this export and subsequent SGs formation.
Chengyu Li+8 more
wiley +1 more source
Contaminant inclusion into protein crystals analyzed by electrospray mass spectrometry and X‐ray crystallography [PDF]
Juan Carlos Fontecilla‐Camps+3 more
openalex +1 more source
Therapeutic Repair of Sperm Quality Decline Caused by Polytetrafluoroethylene
Exposure to PTFE (teflon), a commonly used microplastic in non‐stick cookware, significantly reduces sperm quality in both humans and mice. Specifically, PTFE induces the disruption of sperm cytoskeleton and F‐actin assembly through targeting SKAP2 in haploid spermatid.
Shiming Gan+15 more
wiley +1 more source
Mass spectrometry of large organic ions by electrospray, particle and photon induced desorption: foreword [PDF]
E. F. da Silveira
openalex +1 more source
Translation of a Human‐Based Malaria‐on‐a‐Chip Phenotypic Disease Model for In Vivo Applications
Inoculation of the Malaria‐on‐a‐Chip model with human erythrocytes infected with Plasmodium falciparum can support the entire intraerythrocytic lifecycle for 7 days in vitro. Utilizing this human‐based, serum‐free model provides an alternative to animal testing by introducing a human‐based, preclinical alternative for antimalarial therapeutic delivery.
Michael J. Rupar+15 more
wiley +1 more source
On-Line Capillary Electrophoresis-Electrospray Mass Spectrometry for the Analysis of Pharmaceuticals
Samir Cherkaoui+3 more
openalex +2 more sources
This study reveals that ADAR1, an RNA‐editing enzyme, fine‐tunes immune responses in the placenta by preventing the accumulation of immunogenic double‐stranded RNAs (dsRNAs) from interferon‐stimulated genes. The loss of ADAR1 in the placenta leads to excessive interferon signaling restricted to the junctional zone, disrupting placental development and ...
Xiaogang Chen+7 more
wiley +1 more source
Correction: A planar pentacoordinate oxygen in the experimentally observed [Be<sub>5</sub>O<sub>6</sub>]<sup>2-</sup> dianion. [PDF]
Sun R+5 more
europepmc +1 more source