Results 161 to 170 of about 210,261 (363)

High specific impulse electrospray propulsion with small capillary emitters [PDF]

open access: yesarXiv
This study demonstrates the feasibility of using smaller capillary emitters to achieve higher specific impulse ($I_\text{sp}$) in electrospray propulsion. Four ionic liquids were characterized using capillary emitters with tip diameters from 15 to 50 $\mu$m. Smaller diameter capillaries produced smaller and more stable Taylor cones.
arxiv  

Macrophage WEE1 Directly Binds to and Phosphorylates NF‐κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis

open access: yesAdvanced Science, EarlyView.
The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang   +13 more
wiley   +1 more source

Deuterium exchange of α‐helices and β‐sheets as monitored by electrospray ionization mass spectrometry

open access: green, 1994
David S. Wagner   +4 more
openalex   +1 more source

Artificial Intelligent‐Enhanced Metabolite Profiling for Intraoperative IDH1 Genotyping in Glioma Using an Orthogonally Responsive SERS Probe

open access: yesAdvanced Science, EarlyView.
This study presents a novel approach for intraoperative identification of the IDH1 genotype in glioma patients using a surface‐enhanced Raman scattering (SERS) probe to measure glutathione and hydrogen peroxide. By integrating AI‐driven deep learning algorithms, the method achieves rapid and accurate genotype differentiation, offering the potential to ...
Hang Yin   +14 more
wiley   +1 more source

Determination of the endogenous phosphorylation state of B‐50/GAP‐43 and neurogranin in different brain regions by electrospray mass spectrometry [PDF]

open access: bronze, 1996
Mónica Di Luca   +6 more
openalex   +1 more source

Drug Screening of Primary Human Endometriotic Cells Based on Micro‐Encapsulating Microfluidic Chip

open access: yesAdvanced Science, EarlyView.
To address the challenges of unclear mechanisms and poor therapeutic efficacy in endometriosis (EMs), this study develops a microfluidic chip platform integrated with primary cell‐laden microcapsules. Gradient drug screening reveals individualized treatment response variations among patients and their correlation with clinical outcomes.
Qiong Chen   +5 more
wiley   +1 more source

Contaminant inclusion into protein crystals analyzed by electrospray mass spectrometry and X‐ray crystallography [PDF]

open access: green, 1998
Juan Carlos Fontecilla‐Camps   +3 more
openalex   +1 more source

The E3 Ligase NEDD4L Prevents Colorectal Cancer Liver Metastasis via Degradation of PRMT5 to Inhibit the AKT/mTOR Signaling Pathway

open access: yesAdvanced Science, EarlyView.
Neural precursor cell expressed developmentally down‐regulated gene 4‐like (NEDD4L) prevents colorectal cancer liver metastasis through ubiquitination and degradation of protein arginine methyltransferase 5 (PRMT5). PRMT5 degradation attenuates the methylarginine of AKT1.
Zhewen Dong   +8 more
wiley   +1 more source

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