Results 171 to 180 of about 312,664 (339)

Uric Acid Functions as an Endogenous Modulator of Microglial Function and Amyloid Clearance in Alzheimer's Disease

Advanced Science, EarlyView.
Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie, Qiuyang Zheng, Jiaming Lv, Qian Zhang, Zhiwei Cui, Shuai Huang, Wei Yu, Binyang Chen, Wanling Que, Shanpan Fu, Yuemei Xi, Jiayu Chen, Xueling Ye, Shuyi Chen, Hairong Zhao, Tetsuya Yamamoto, Hidenori Koyama, Xin Wang, Jidong Cheng   +18 more
wiley   +1 more source

Needle‐free, Liquid Metal‐embedded Electrospray Deposition System for Controlled Microdroplet Printing

Advanced Science, EarlyView.
The liquid metal‐embedded electrospray deposition (LM‐ESD) system combines stable droplet spray, clog‐free and recoverable operation, and simplified fabrication in a single polydimethylsiloxane (PDMS) microfluidic platform. By eliminating external electrodes, it offers needle‐free, robust, and scalable droplet array printing, ensuring reproducibility ...
Chaeyeong Kang, Seokbeom Roh, Hyunjun Park, Sugeun Lee, Taeha Lee, Sang Won Lee, Hansung Kim, Jinsung Park, Gyudo Lee, Insu Park   +9 more
wiley   +1 more source

Electrospray tandem mass spectrometry of 2 H ‐chromenes

, 2004
M. Rosário Domingues, Pedro Domíngues, Maria Manuel Oliveira, Luís M. Carvalho, Ana F. Oliveira‐Campos, A. J. Ferrer Correia   +5 more
openalex   +2 more sources

Temperature Thresholds Govern Microbial‐Mediated Dissolved Organic Carbon Dynamics in Coastal Ecosystems

Advanced Science, EarlyView.
Coastal dissolved organic carbon (DOC) represents one of the largest reduced carbon pools on Earth, and they are influenced by temperature. Across 7.6–35.9 °C ranges, the microbial‐mediated DOC dynamics is characterized by three temperature thresholds.
Junfu Dong, Xiao Chen, Fangshuai Chen, Zhenzhen Hu, Qichao Tu, Gang Li, Chen He, Quan Shi, Qiang Zheng, Feng Chen, Tuo Shi, Nianzhi Jiao, Jihua Liu   +12 more
wiley   +1 more source

Compositional Analysis of Adsorbed Organic Aerosol on a Microresonator Mass Sensor [PDF]

, 2018
Campbell, Steven J., Giorio, Chiara, Jones, Roderic L., Kalberer, Markus, Seshia, Ashwin A., Zielinski, Arthur T.   +5 more
core   +1 more source

Improved Sensitivity in Hydrophilic Interaction Liquid Chromatography-Electrospray-Mass Spectrometry after Removal of Sodium and Potassium Ions from Biological Samples [PDF]

, 2021
Ida Erngren, Marika Nestor, Curt Pettersson, Mikael Hedeland   +3 more
openalex   +1 more source

Novel Antifungal Scaffold Targeting Tubulin Overcomes Sclerotinia Sclerotiorum Resistance

Advanced Science, EarlyView.
Addressing pesticide resistance, novel chromone‐acylhydrazone hybrids targeting fungal tubulin are synthesized. Compound G24 potently inhibited S. sclerotiorum (EC50 = 0.21µg mL−1) and demonstrated enhanced field performance via microencapsulation, offering a sustainable strategy against resistance and for global food security.
Lihui Shao, Xianqun Hu, Ying Wu, Xiang Zhou, Bo Zhang, Song Yang   +5 more
wiley   +1 more source

Click-and-Analyze: Automated Pinpoint Ambient Mass Spectrometry with Sheath-Flow Probe Electrospray Ionization. [PDF]

Mass Spectrom (Tokyo)
Li L, Xie Q, Chen LC, Ninomiya S.
europepmc   +1 more source

Intestinal Neutral Ceramidase Deficiency Triggers Regulatory T Cell Response via Gd3 to Protect the Host from Intestinal Inflammation

Advanced Science, EarlyView.
Deletion of ASAH2 in intestinal epithelial cells induces the accumulation of ganglioside GD3 via regulating ST8SIA1. GD3 is identified as the glycolipid ligand for the inhibitory receptor Siglec‐E on macrophages. GD3/Siglec‐E ligation polarizes macrophages and promotes the proliferation of colonic ST2+ T regulatory cells via the induction of IL‐33. The
Zhishan Xu, Chao Lei, Mukesh K Sriwastva, Ting Wang, Amanguli Tuohongerbieke, Xiaotong Song, Collin Noud, Shannon Derkson, Yi Tan, Gerald Dryden, Craig J McClain, Zhongbin Deng   +11 more
wiley   +1 more source

Electrospray [PDF]

, 2019
openaire   +1 more source